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5,5-heteroaromatic anti-infective compounds

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posted on 2017-08-01, 00:00 authored by Garrett C. Moraski, Marvin J MillerMarvin J Miller
The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,1-b]thiazole-5-carbox- amide.

History

Patent Number

US 9605002 B2

Other Application

14/415,726

Inventor

Garrett C. Moraski Marvin J. Miller

Inventor from Local Institution

Garrett C. Moraski Marvin J. Miller

Assignee

University of Notre Dame du Lac

Date Modified

2017-08-01

Language

  • English

Claims

20

Prior Publication Number

US 20150210715 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 513/04 (20130101); A61K 9/0014 (20130101); A61K 9/0019 (20130101); A61K 9/2059 (20130101); A61K 9/2866 (20130101); A61K 31/4188 (20130101

Contributor

Garrett C. Moraski|Marvin J. Miller

International Patent Classification Codes

C07D 513/04 (20060101); A61K 31/4188 (20060101); A61K 9/00 (20060101); A61K 9/28 (20060101); A61K 9/20 (20060101)

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