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Anti-cancer compounds, synthesis thereof, and methods of using same

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posted on 2016-06-07, 00:00 authored by Garrett C. Moraski, Jonathan Stefely, Marvin J MillerMarvin J Miller
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in a subject, such as using the disclosed heterocyclic anti-cancer agents.

History

Patent Number

US 8268874 B2

Other Application

12/920,808

Inventor

Marvin J. Miller Garrett C. Moraski Jonathan Stefely

Inventor from Local Institution

Marvin J. Miller Garrett C. Morasaki Jonathan Stefely

Assignee

University of Notre Dame Du Lac

Date Modified

2017-08-01

Language

  • English

Claims

41

Prior Publication Number

US 20110021574 A1

Publisher

United States Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 249/04 (20130101); C07D 401/12 (20130101); C07D 413/12 (20130101)

Contributor

Marvin J. Miller|Garrett C. Morasaki|Jonathan Stefely

International Patent Classification Codes

A61K 31/422 (20060101); C07D 263/34 (20060101)

US Patent Classification Codes

C07D 249/04 (20060101); C07D 401/12 (20060101)

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