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Bone and tissue scaffolding for delivery of therapeutic agents

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posted on 2016-06-07, 00:00 authored by Dale R. Sumner, Glen L. Niebur, Steven R. Schmid
The present invention provides a bone in-growth surface for implants which has a structure for delivering therapeutic agents to surrounding bone and tissue. The bone in-growth surface may comprise scaffolding and a controlled-permeability layer which contains the therapeutic agents in a variety of reservoirs. The porosity of the scaffolding may be controllable from zero porosity to essentially a fully porous material.

History

Patent Number

US 7674477 B2

Other Application

11/325,530

Inventor

Steven R. Schmid Glen L. Niebur Dale R. Sumner

Inventor from Local Institution

Steven R. Schmid Niebur Glen L.

Assignee

University of Notre Dame Du Lac

Date Modified

2016-06-07

Language

  • English

Claims

40

Publisher

United States Patent and Trademark Office

Cooperative Patent Classification Codes

A61F 2/28 (20130101); A61L 27/56 (20130101); A61F 2/30965 (20130101); A61F 2002/30006 (20130101); A61F 2002/30011 (20130101); A61F 2002/30062 (20130101); A61F 2002/30064 (20130101); A61F 2002/30087 (20130101); A61F 2002/30092 (20130101); A61F 2002/30677 (20130101); A61F 2002/3092 (20130101); A61F 2002/30925 (20130101); A61F 2002/30948 (20130101); A61F 2002/30957 (20130101); A61F 2002/30967 (20130101); A61F 2002/3097 (20130101); A61F 2002/30971 (20130101); A61F 2002/30978 (20130101); A61F 2210/0004 (20130101); A61F 2210/0014 (20130101); A61F 2250/0015 (20130101); A61F 2250/0023 (20130101); A61F 2310/00017 (20130101); A61F 2310/00023 (20130101); A61F 2310/00029 (20130101); A61F 2310/00041 (20130101); A61F 2310/00059 (20130101); A61F 2310/00131 (20130101); A61F 2310/00203 (20130101); A61F 2310/00239 (20130101); A61F 2310/00293 (20130101); A61F 2310/00395 (20130101); A61F 2310/0058 (20130101); A61F 2310/00592 (20130101); A61F 2310/00604 (20130101); A61F 2310/00796 (20130101); A61F 2310/0097 (20130101)

Contributor

Steven R. Schmid|Niebur Glen L.

International Patent Classification Codes

A61K 9/22 (20060101); A61F 2/02 (20060101)

US Patent Classification Codes

424/422; 424/423; 424/424; 424/425; 424/427; 604/890.1; 604/891.1;

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