High-affinity DMF5 T cell receptor (TCR) variants

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posted on 2017-11-29, 00:00 authored by Brian G. Pierce, Brian M. Baker, Zhiping Weng

High-affinity variants of the DMF5 TCR, and methods of use thereof for the treatment and imaging of cancer in a patient.

History

Patent Number

US 9717758 B2

Other Application

14/280,308

USPTO Link

http://patft1.uspto.gov/netacgi/nph-Parser?patentnumber=9717758

Inventor

Brian G. Pierce Zhiping Weng Brian M. Baker

Inventor from Local Institution

Brian M. Baker

Assignee

University of Notre Dame du Lac University of Massachusetts (Boston, MA)

Date Modified

2017-11-29

Language

English

Claims

20

Prior Publication Number

US 20140341809 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

A61K 35/17 (20130101); C07K 14/705 (20130101)

Contributor

Brian M. Baker

International Patent Classification Codes

A61K 39/395 (20060101); C07K 14/705 (20060101); A61K 35/17 (20150101)

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