University of Notre Dame
Browse
9,333,222 OCR.pdf (1.14 MB)

Histone deacetylase inhibitors as therapeutic agents for Niemann-Pick type C disease

Download (1.14 MB)
standard
posted on 2017-08-01, 00:00 authored by Frederick R. Maxfield, Olaf G. Wiest, Paul Helquist
Embodiments herein relate to the field of lysosomal storage disorders, and, more specifically, to methods of treating lysosomal storage disorders such as Niemann-Pick type C disease, for instance with inhibitors of histone deacetylases, particularly inhibitors of class 1 histone deacetylases. In various embodiments, methods of treating Niemann-Pick type C disease with inhibitors of class 1 histone deacetylases are described.

History

Patent Number

US 9333222 B2

Other Application

12/888,267

Inventor

Olaf G. Wiest Frederick R. Maxfield Paul Helquist

Inventor from Local Institution

Olaf G. Wiest Paul Helquist

Assignee

University of Notre Dame du Lac Cornell University (Ithaca, NY)

Date Modified

2017-08-01

Language

  • English

Claims

10

Prior Publication Number

US 20110071109 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

A61K 31/721 (20130101); A61K 31/724 (20130101); A61K 47/48092 (20130101); A61K 31/715 (20130101); A61K 31/4045 (20130101); A61K 31/165 (20130101)

Contributor

Olaf G. Wiest|Paul Helquist

International Patent Classification Codes

A61K 31/165 (20060101); A61K 31/4045 (20060101); A61K 31/724 (20060101); A61K 47/48 (20060101); A61K 31/721 (20060101)

Usage metrics

    Patents

    Categories

    No categories selected

    Keywords

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC