Inhibitors of matrix metallaproteinases

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posted on 2016-06-07, 00:00 authored by Masahiro Ikejiri, Mayland ChangMayland Chang, Mijoon Lee, Rafael Fridman, Shahriar MobasheryShahriar Mobashery

The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.

History

Patent Number

US 7928127 B2

Other Application

11/914,933

USPTO Link

http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/7928127

Inventor

Mijoon Lee Masahiro Ikejiri Mayland Chang Rafael Fridman Shahriar Mobashery

Inventor from Local Institution

Mayland Chang Shahriar Mobashery

Assignee

University of Notre Dame Du Lac

Date Modified

2016-06-07

Language

English

Claims

20

Prior Publication Number

US 20090005420 A1

Publisher

United States Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 303/34 (20130101); C07D 331/02 (20130101); C07D 407/06 (20130101); C07D 409/06 (20130101); C07F 9/65586 (20130101); C07F 9/564 (20130101); C07F 9/65505 (20130101); C07F 9/655309 (20130101); C07D 409/12 (20130101)

Contributor

Mayland Chang|Shahriar Mobashery

International Patent Classification Codes

A61K 31/4427 (20060101); A61K 31/336 (20060101); C07D 331/02 (20060101); A61K 31/38 (20060101); C07D 303/34 (20060101); C07D 409/02 (20060101)

US Patent Classification Codes

514/336; 514/430; 514/475; 546/279.7; 549/556; 549/90;

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Licence

CC BY 4.0

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