Inhibitors of matrix metallaproteinases

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posted on 2016-06-07, 00:00 authored by Masahiro Ikejiri, Mayland ChangMayland Chang, Mijoon Lee, Rafael Fridman, Shahriar MobasheryShahriar Mobashery

The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.

History

Related Materials

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URL - References http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/7928127

Patent Number

US 7928127 B2

Other Application

11/914,933

USPTO Link

http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/7928127

Inventor

Mijoon Lee Masahiro Ikejiri Mayland Chang Rafael Fridman Shahriar Mobashery

Inventor from Local Institution

Mayland Chang Shahriar Mobashery

Assignee

University of Notre Dame Du Lac

Date Modified

2016-06-07

Language

English

Claims

20

Prior Publication Number

US 20090005420 A1

Publisher

United States Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 303/34 (20130101); C07D 331/02 (20130101); C07D 407/06 (20130101); C07D 409/06 (20130101); C07F 9/65586 (20130101); C07F 9/564 (20130101); C07F 9/65505 (20130101); C07F 9/655309 (20130101); C07D 409/12 (20130101)

Contributor

Mayland Chang|Shahriar Mobashery

International Patent Classification Codes

A61K 31/4427 (20060101); A61K 31/336 (20060101); C07D 331/02 (20060101); A61K 31/38 (20060101); C07D 303/34 (20060101); C07D 409/02 (20060101)

US Patent Classification Codes

514/336; 514/430; 514/475; 546/279.7; 549/556; 549/90;