Inhibitors of matrix metalloproteinases

https://doi.org/10.7274/24859335

standard

posted on 2016-06-07, 00:00 authored by Masahiro Ikejiri, Mayland ChangMayland Chang, Mijoon Lee, Rafael Fridman, Shahriar MobasheryShahriar Mobashery

The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.

History

Related Materials

1.
URL - References http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/8093287

Publisher

United States Patent and Trademark Office

Date Modified

2016-06-07

Contributor

Mijoon Lee|Shahriar Chang Mayland|Mobashery

Language

English

Patent Number

US 8093287 B2

Other Application

13/047,605

USPTO Link

http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/8093287

Inventor

Mijoon Lee Masahiro Ikejiri Mayland Chang Rafael Fridman Shahriar Mobashery

Inventor from Local Institution

Mijoon Lee Shahriar Chang Mayland Mobashery

Assignee

University of Notre Dame Du Lac Wayne State University (Detroit, MI)

Claims

20

Prior Publication Number

US 20110224275 A1

Cooperative Patent Classification Codes

C07D 303/34 (20130101); C07D 331/02 (20130101); C07D 407/06 (20130101); C07D 409/06 (20130101); C07D 409/12 (20130101); C07F 9/564 (20130101); C07F 9/65505 (20130101); C07F 9/655309 (20130101); C07F 9/65586 (20130101)

International Patent Classification Codes

A61K 31/38 (20060101); C07D 331/02 (20060101)

US Patent Classification Codes

514/430; 549/90;