US8513290.pdf (3.89 MB)
Method for preparing largazole analogs and uses thereof
standardposted on 2016-06-07, 00:00 authored by Albert A. Bowers, James E. Bradner, Olaf G. Wiest, Robert M. Williams, Tenaya L. Newkirk
Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described.
Patent NumberUS 8513290 B2
InventorRobert M. Williams James E. Bradner Albert A. Bowers Tenaya L. Newkirk Olaf G. Wiest
Inventor from Local InstitutionOlaf Wiest
AssigneeUniversity of Notre Dame Du Lac Colorado State University Research Foundation (Fort Collins, CO) Dana-Farber Cancer Institute, Inc. (Boston, MA)