Optical-quality surface that imparts spatial control of macrophage fusion

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posted on 2022-01-16, 00:00 authored by James Faust, Kyle Doudrick, Robert Ros, Tatiana Ugarova, Wayne Christenson

Methods to form a surface coating and surface pattern, which are based on adsorption of hydrocarbon chains that can be used with imaging optics to visualize macrophage fusion and multinucleated giant cell formation with living specimens are described.

History

Patent Number

US 10801016 B2

Other Application

15/699,974

USPTO Link

http://patft1.uspto.gov/netacgi/nph-Parser?patentnumber=10801016

Inventor

James Faust Tatiana Ugarova Robert Ros Wayne Christenson Kyle Doudrick

Inventor from Local Institution

Kyle Doudrick

Assignee

Arizona State University (Scottsdale, AZ) University of Notre Dame du Lac

Date Modified

2022-02-04

Language

English

Claims

15

Prior Publication Number

US 2018/0066234 A1

Cooperative Patent Classification Codes

02B 21/34 (20130101); G01N 33/5055 (20130101); C12M 25/00 (20130101); C12M 23/20 (20130101); G01N 33/5032 (20130101); C12N 5/16 (20130101); C12N 5/0645 (20130101); G01N 33/5005 (20130101); C12N 2533/12 (20130101); C12N 2537/00 (20130101); C12N 2535/10 (20130101); C12N 2535/00 (20130101); C12N 2539/00 (20130101); C12N 2533/20 (20130101)

Contributor

Kyle Doudrick

International Patent Classification Codes

G02B 21/34 (20060101); G01N 33/50 (20060101); C12M 1/12 (20060101); C12M 1/00 (20060101); C12N 5/16 (20060101); C12N 5/0786 (20100101)