Regulation of cholesterol homeostasis
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posted on 2017-07-31, 00:00 authored by Richard E. TaylorThe invention provides novel compounds of Formulas (I)-(IV), as described herein. Also provided are compositions of these compounds, method of making the compounds, and methods of using the compounds. The compounds can be used to regulate cholesterol homeostasis and to treat conditions and diseases associated with cholesterol homeostasis, including lysosomal lipid storage disorders such as Niemann-Pick Disease type C.
History
Patent Number
US 8865761 B1Other Application
13/961,659Inventor
Richard E. TaylorInventor from Local Institution
Richard E. TaylorAssignee
University of Notre Dame du LacDate Modified
2017-08-01Language
- English
Claims
18Prior Publication Number
61742290Publisher
U.S. Patent and Trademark OfficeCooperative Patent Classification Codes
C07D 407/06 (20130101); C07D 303/14 (20130101); C07D 309/06 (20130101); C07D 303/28 (20130101); A61K 31/351 (20130101); A61K 31/365 (20130101); A61K 9/0014 (20130101); A61K 9/0019 (20130101); A61K 47/02 (20130101); A61K 47/10 (20130101); A61K 47/32 (20130101); A61K 9/12 (20130101); A61K 9/2054 (20130101); A61K 9/4858 (20130101)Contributor
Richard E. TaylorInternational Patent Classification Codes
A61K 31/335 (20060101); A61K 31/351 (20060101)US Patent Classification Codes
514/450; 514/451Usage metrics
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