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Selective matrix metalloproteinase inhibitors

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posted on 2018-08-07, 00:00 authored by Mayland ChangMayland Chang, Shahriar MobasheryShahriar Mobashery
The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinases (MMPs). The compounds can be selective MMP inhibitors, for example, selective inhibitors of MMP-2, MMP-9, and/or MMP-14. The disease, disorder, or condition can include, for example, stroke, neurological disorders, ophthalmological disorders, or wounds, such as chronic wounds or diabetic wounds.

History

Patent Number

US 9951035 B2

Other Application

15/469,010

Inventor

Mayland Chang Shahriar Mobashery

Inventor from Local Institution

Mayland Chang Shahriar Mobashery

Assignee

University of Notre Dame Du Lac

Date Modified

2018-08-07

Language

  • English

Claims

19

Prior Publication Number

US 20170190685 A1

Publisher

U.S. Patent and Trademark Office

Cooperative Patent Classification Codes

C07D 413/12 (20130101); C07D 331/02 (20130101); A61K 9/0014 (20130101); A61K 31/38 (20130101); A61K 31/4245 (20130101); C07D 303/34 (20130101)

Contributor

Mayland Chang|Shahriar Mobashery

International Patent Classification Codes

C07D 331/02 (20060101); A61K 9/00 (20060101); A61K 31/38 (20060101); C07D 413/12 (20060101); C07D 303/34 (20060101); A61K 31/4245 (20060101)

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