Aerospace and Mechanical Engineering
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- Author(s):
- Andrew A. Oliva, Aleksandar Jemcov
- Abstract:
Modeling variable specific heat is a crucial aspect of aerospace engineering, playing a significant role in designing and analyzing high-enthalpy internal and external flows. Moreover, variable specific heat effects are becoming progressively more important with the increasing interest in hypersonic flight, where accurate temperature prediction is critical to determine chemical reaction rates and heat flux. Similarly, the influence of variable specific heat is significant in combustion, where…
- Date Created:
- 2023-09-19
- Record Visibility:
- Public
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- Author(s):
- Bradley Ellis, Aylin Acun, U. Isik Can, Pinar Zorlutuna
- Abstract:
The heart wall tissue, or the myocardium, is one of the main targets in cardiovascular disease prevention and treatment. Animal models have not been sufficient in mimicking the human myocardium as evident by the very low clinical translation rates of cardiovascular drugs. Additionally, current in vitro models of the human myocardium possess several shortcomings such as lack of physiologically relevant co-culture of myocardial cells, lack of a 3D biomimetic environment, and the use of non-huma…
- Date Published:
- 2017-03
- Record Visibility:
- Public
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- Author(s):
- Shirou Lou, Jarrod Schiffbauer, Tengfei Lou
- Abstract:
In this work, the droplet size in a water-in-oil emulsion obtained by supersaturation is studied. The emulsion is obtained by cooling down a saturated water/oil solution by a certain temperature difference. The effects of the cooling rate and temperature difference on the produced droplet size are experimentally investigated. The average size of water droplets in the emulsion is found to be proportional to the square root of the cooling rate. By analyzing the time scales of three different st…
- Date Published:
- 2017-10
- Record Visibility:
- Public
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- Author(s):
- Yide Zhang, Prakash Nallathamby, Genevieve D. Vigil, Aamir A. Khan, Devon E. Mason, Joel D. Boerckel, Ryan K. Roeder, Scott S. Howard
- Abstract:
Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the super-resolution microscopy is not feasible in many applications. In this paper, we propose and demonstrate a saturation-based super-resolution fluorescence microscopy technique that can be easily implemented and requires neither additional hardware nor complex post-processin…
- Date Published:
- 2018-04
- Record Visibility:
- Public
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- Author(s):
- Cody E. Narcisco, Nicholas M. Contento, Thomas J. Storey, David J. Hoelzle, Jeremiah J. Zartman
- Abstract:
Mechanical forces are critical but poorly understood inputs for organogenesis and wound healing. Calcium ions (Ca2+) are critical second messengers in cells for integrating environmental and mechanical cues, but the regulation of Ca2+ signaling is poorly understood in developing epithelial tissues. Here we report a chip-based regulated environment for microorgans that enables systematic investigations of the crosstalk between an organ’s mechanical stress environment and biochemical signaling …
- Date Published:
- 2017-07
- Record Visibility:
- Public