Chemical and Biomolecular Engineering

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  • Inventor(s):
    Hsueh-Chia Chang, Shau-Chun Paul Wang, Dmitri Lastochkin, Leslie Yeo, Zachary Gagnon
    Patent Number:
    US 8267914 B1
    Description:

    The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, oste…

    Date Issued:
    2012-09-18
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Zachary Gagnon, Hsueh-Chia Chang
    Patent Number:
    US 7744738 B2
    Description:

    The present invention provides a method and apparatus for use in rapid particle transportation, separation, focusing, characterization, and release. Dielectrophoresis and electro-osmotic driven fluid convection are used independently or in tandem as the driving forces for particle manipulation and on occasion characterization. Although dielectrophoresis has been acknowledged for decades as a powerful technique for particle manipulation and characterization, long processing times and measureme…

    Date Issued:
    2010-06-29
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Hsueh-Chia Chang, Jason Gordon, Satyajyoti Senapati, Zachary Gagnon, Sagnik Basuray
    Patent Number:
    US 8771938 B2
    Description:

    Disclosed are example methods and devices for detecting one or more targets. An example method includes placing a sample including a first target with in a microfluidic device and hybridizing a plurality of copies of the first target with a plurality of nanostructures. The example method includes applying an electric current to the plurality of nanostructures and using an electric field created by the electric current to move the plurality of nanostructures. In addition, the plurality of nano…

    Date Issued:
    2014-07-08
    Record Visibility:
    Public
    Resource Type
    Patent