Chemical and Biomolecular Engineering

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  • Inventor(s):
    Z. Basar Bilgicer, Tanyel Kiziltepe Bilgicer, Jonathan D. Ashley, Jared Stefanick, Nathan J. Alves, Michael W. Handlogten
    Patent Number:
    US 9872870 B2

    Embodiments provide systems, methods, and compositions for nanoparticle-based drug delivery to target cells or tissues. A drug delivery system may include a nanoparticle with a targeting component and a therapeutic component. The nanoparticle may have a predetermined number or valence of targeting molecules for multivalent interaction with a target cell or tissue. Binding of the targeting molecules to the target cell may result in receptor-mediated uptake of the nanoparticle by the target cel…

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