Chemical and Biomolecular Engineering

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  • Author:
    David T. Omstead
    Advisory Committee:
    Mark McCready, Edward Maginn, David Leighton, Başar Bilgiçer
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-01-17
    Record Visibility:
    Public
  • Author:
    Yolanda Bonita
    Advisory Committee:
    Casey P. O'Brien, William F. Schneider, Thomas F. Degnan, Jason C. Hicks
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-10-09
    Record Visibility:
    Public
  • Author:
    Vikramjit Singh Rathee
    Advisory Committee:
    Jonathan Whitmer
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-05-03
    Record Visibility:
    Public
  • Author:
    Garrison M. Crouch
    Advisory Committee:
    Merlin Bruening, David Go, Susan Fullerton-Shirey, Paul Bohn, Paul McGinn
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-04-05
    Record Visibility:
    Public
  • Author:
    Jacob J. Gerace
    Advisory Committee:
    Edward Maginn, Jonathan Whitmer, Alexander Dowling
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    Master of Science in Chemical Engineering
    Defense Date:
    2019-03-25
    Record Visibility:
    Public
  • Author(s):
    Pavel A. Brodkiy, Qinfeng Wu, Francisco J. Huizar, Dharsan K. Soundarrajan, Cody Narciso, Megan evis, Ninfamaria Arredondo-Walsh, Jianxu Chen, Peixian Liang, Danny Z. Chen, Jeremiah James Zartman
    Abstract:

    Organ development is driven by a set of patterned inductive signals. However, how these signals are integrated to coordinate tissue patterning is still poorly understood. Calcium ions (Ca2+) are critical signaling components involved in signal integration and are regulated by a core Ca2+ signaling toolkit. Ca2+ signaling encodes a significant fraction of information in cells through both amplitude and frequency-dependent regulation of transcription factors and key regulatory enzymes. A range …

    Date Published:
    2017-09
    Record Visibility:
    Public
  • Author(s):
    Cody E. Narcisco, Nicholas M. Contento, Thomas J. Storey, David J. Hoelzle, Jeremiah J. Zartman
    Abstract:

    Mechanical forces are critical but poorly understood inputs for organogenesis and wound healing. Calcium ions (Ca2+) are critical second messengers in cells for integrating environmental and mechanical cues, but the regulation of Ca2+ signaling is poorly understood in developing epithelial tissues. Here we report a chip-based regulated environment for microorgans that enables systematic investigations of the crosstalk between an organ’s mechanical stress environment and biochemical signaling …

    Date Published:
    2017-07
    Record Visibility:
    Public
  • Author(s):
    Qinfeng Wu, Pavel Aleksandrovich Brodkiy, Francisco Javier Huizar, Jamison John Jangula, Cody Narciso, Megan Kathleen Levis, Teresa Brito-Robinson, Jeremiah J. Zartman
    Abstract:

    Recently, organ-scale intercellular Ca2+ transients (ICTs) were reported in the Drosophila wing disc. However, the functional in vivo significance of ICTs remains largely unknown. Here we demonstrate the in vivo relevance of intercellular Ca2+ signaling and its impact on wing development. We report that Ca2+ signaling in vivo decreases as wing discs mature. Ca2+ signaling ex vivo responds to fly extract in a dose-dependent manner. This suggests ICTs occur in vivo due to chemical stimulus that…

    Date Published:
    2017-09
    Record Visibility:
    Public
  • Author:
    Gray Laughlin
    Advisory Committee:
    William F. Schneider
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    MSChE
    Defense Date:
    2018-07-02
    Record Visibility:
    Public
  • Author:
    Christopher Eugene Shuck
    Advisory Committee:
    Davide Hill, Joseph Powers, Alexander S. Mukasyan, Paul McGinn
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    PhD
    Defense Date:
    2017-11-17
    Record Visibility:
    Public
  • Author:
    Sherwood Benavides
    Advisory Committee:
    William A Phillip
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    PhD
    Defense Date:
    2017-07-19
    Record Visibility:
    Public
  • Author:
    Steven Marczak
    Advisory Committee:
    Hsueh-Chia Chang, Paul Bohn, Basar Bilgicer, William Phillip
    Degree Area:
    Chemical and Biomolecular Engineering
    Degree:
    PhD
    Defense Date:
    2017-07-27
    Record Visibility:
    Public