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  • Inventor(s):
    Shuang Luan, Danny Z. Chen, Xiaobo Sharon Hu, Chao Wang, Xiaodong Wu
    Patent Number:
    US 7283611 B2
    Description:

    The present invention provides a method comprising recursively partitioning an intensity modulated beam into plateaus; and partitioning the plateaus into segments. The present invention also provides a method for controlling administration of radiation therapy to a patient based on static leaf prescriptions. In addition, the present invention provides a method for partitioning an IMB.

    Date Issued:
    2007-10-16
    Resource Type
    Patent
  • Inventor(s):
    Shuang Luan, Danny Z. Chen, Xiaobo Sharon Hu, Chao Wang, Xiaodong Wu
    Patent Number:
    US 7466797 B2
    Description:

    The present invention provides a method comprising the following steps: (a) partitioning an intensity modulated beam into a set of sub-IMBs; and (b) partitioning the sub-IMBs into segments, wherein steps (a) and (b) introduce no machine delivery error. The present invention also provides a method comprising the following steps: (a) recursively partitioning an intensity modulated beam into plateaus; and (b) partitioning the plateaus into segments, wherein step (a) comprises determining a trade…

    Date Issued:
    2008-12-16
    Resource Type
    Patent
  • Inventor(s):
    Xiaobo Sharon Hu, Cedric X. Yu, Bo Zhou, Danny Z. Chen, Kevin Whitton
    Patent Number:
    US 8494115 B2
    Description:

    Disclosed is an example method to calculate radiation dose. The method includes receiving a tissue matrix in which the tissue matrix includes a plurality of voxels. The example method also includes producing a first plurality of transport lines with a direction controller in which each transport line is indicative of a cone of irradiated energy, and calculating at least one radiation dose with at least one deposit engine substantially in parallel with producing a second plurality of transport…

    Date Issued:
    2013-07-23
    Resource Type
    Patent
  • Inventor(s):
    Cedric X. Yu, Shuang Luan, Danny Z. Chen, Matthew A. Earl, Chao Wang
    Patent Number:
    US 8014494 B2
    Description:

    Provided herein are methods and systems for designing a radiation treatment for a subject using single arc dose painting. The methods and systems comprise an algorithm or a computer-readable product having the same, to plan the radiation treatment. The algorithm converts pairs of multiple leaf collimation (MLC) leaves to sets of leaf aperture sequences that form a shortest path single arc thereof where the pairs of MLC leaves each aligned to an intensity profile of densely-spaced radiation be…

    Date Issued:
    2011-09-06
    Resource Type
    Patent
  • Inventor(s):
    Kang Li, Xiaodong Wu, Danny Z. Chen, Milan Sonka
    Patent Number:
    US 7995810 B2
    Description:

    A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations.

    Date Issued:
    2011-08-09
    Resource Type
    Patent
  • Inventor(s):
    John DeWolfe MacKenzie, Jiazhuo Wang, Danny Z. Chen, Rageshree Ramachandran
    Patent Number:
    US 10121245 B2
    Description:

    Systems and methods are provided for identifying markers for inflammation in a tissue image. The tissue image is captured as an image of a histology slide. Subcellular structures in the tissue image are segmented via a first automated process to identify at least one variety of immune cells within the image. Glands and vilii are identified within the tissue image via a second automated process. Neutrophils are identified within the tissue image via a third automated process. An output represe…

    Date Issued:
    2018-11-06
    Resource Type
    Patent