Electrical Engineering

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  • Author:
    Umamaheswara Rao Tida
    Advisory Committee:
    Sungkyu Lim, Suman Datta, Yiyu Shi, Xiaobo Sharon Hu
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-05-09
  • Author:
    Cristobal Alessandri
    Advisory Committee:
    Alan C. Seabaugh, Angel Abusleme, Dani Guzmán
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-04-10
  • Author:
    Etika Agarwal
    Advisory Committee:
    Hai Lin, Vijay Gupta, Panos J. Antsaklis, Bill Goodwine
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-03-26
  • Author:
    Ke Feng
    Advisory Committee:
    Martin Haenggi
    Degree Area:
    Electrical Engineering
    Degree:
    Master of Science in Electrical Engineering
    Defense Date:
    2019-03-20
  • Author:
    Yuan Tian
    Advisory Committee:
    Douglas C. Hall
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-03-29
  • Author:
    Yang Yan
    Advisory Committee:
    Panos Antsaklis
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-03-29
  • Author:
    Donya Ghavidel Dobakhshari
    Advisory Committee:
    Vijay Gupta
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-01-18
  • Author:
    Gerardo Silva-Oelker
    Advisory Committee:
    Patrick Fay
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2019-01-15
  • Author(s):
    Yide Zhang
    Abstract:

    Multiphoton microscopy combined with fluorescence lifetime imaging microscopy (MPM-FLIM) is a technique that allows for imaging the lifetime of fluorescence created by two-photon excitation. It not only possesses the advantages of MPM such as large imaging depth, but also the strengths of FLIM including the ability to discriminate different fluorophores with similar emission spectra. In FLIM, the frequency-domain (FD) method, which relies on periodic intensity-modulated excitation light and i…

    Date Created:
    2015-10-22
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    In cancer and all biomedical researches, we always need a microscope with better imaging precision, speed, functionality, and depth, so that the diagnostics and treatments of cancer and other diseases can be accurate, fast, and noninvasive. However, conventional fluorescence microscopes cannot satisfy these needs due to physical limits on resolution, speed, information, and depth. In this work, we aim to overcome these limits using novel super-resolution microscopy and high-speed quantitative…

    Date Created:
    2018-04-09
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Multiphoton microscopy (MPM) is a widely used in vivo imaging technique in biological and medical applications. In the case of two-photon excitation fluorescence, two lower-energy photons excite a fluorophore which in turn emits a single higher-energy photon, whose rate depends quadratically on the excitation intensity, thus enabling higher resolution with narrower point spread function (PSF) than conventional one-photon fluorescence microscopy. Fluorescence lifetime imaging microscopy (FLIM)…

    Date Created:
    2016-04-04
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    To fundamentally understand biological and medical phenomena such as aging and diseases, we need the information of the microenvironment surrounding living cells. We propose the multiphoton fluorescence lifetime imaging microscopy (MPM-FLIM) platform with super-sensitivity and super-resolution capabilities to quantitatively obtain this information at the intracellular level. First, we present a simple MPM oxygen imaging probe compatible with aqueous biological media based on water-soluble rut…

    Date Created:
    2017-03-30
    Resource Type
    Presentation