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  • Author(s):
    Pavel A. Brodkiy, Qinfeng Wu, Francisco J. Huizar, Dharsan K. Soundarrajan, Cody Narciso, Megan evis, Ninfamaria Arredondo-Walsh, Jianxu Chen, Peixian Liang, Danny Z. Chen, Jeremiah James Zartman
    Abstract:

    Organ development is driven by a set of patterned inductive signals. However, how these signals are integrated to coordinate tissue patterning is still poorly understood. Calcium ions (Ca2+) are critical signaling components involved in signal integration and are regulated by a core Ca2+ signaling toolkit. Ca2+ signaling encodes a significant fraction of information in cells through both amplitude and frequency-dependent regulation of transcription factors and key regulatory enzymes. A range …

    Date Published:
    2017-09
  • Author(s):
    Cody E. Narcisco, Nicholas M. Contento, Thomas J. Storey, David J. Hoelzle, Jeremiah J. Zartman
    Abstract:

    Mechanical forces are critical but poorly understood inputs for organogenesis and wound healing. Calcium ions (Ca2+) are critical second messengers in cells for integrating environmental and mechanical cues, but the regulation of Ca2+ signaling is poorly understood in developing epithelial tissues. Here we report a chip-based regulated environment for microorgans that enables systematic investigations of the crosstalk between an organ’s mechanical stress environment and biochemical signaling …

    Date Published:
    2017-07
  • Author(s):
    Qinfeng Wu, Pavel Aleksandrovich Brodkiy, Francisco Javier Huizar, Jamison John Jangula, Cody Narciso, Megan Kathleen Levis, Teresa Brito-Robinson, Jeremiah J. Zartman
    Abstract:

    Recently, organ-scale intercellular Ca2+ transients (ICTs) were reported in the Drosophila wing disc. However, the functional in vivo significance of ICTs remains largely unknown. Here we demonstrate the in vivo relevance of intercellular Ca2+ signaling and its impact on wing development. We report that Ca2+ signaling in vivo decreases as wing discs mature. Ca2+ signaling ex vivo responds to fly extract in a dose-dependent manner. This suggests ICTs occur in vivo due to chemical stimulus that…

    Date Published:
    2017-09
  • Inventor(s):
    Mark Muldoon, Joan F. Brennecke, Edward J. Maginn, Eric F. V. Scriven, Colin H. McAteer
    Patent Number:
    US 7687513 B2
    Description:

    Disclosed herein are aminopyridinium cations and compositions containing these cations. Piperidino pyridinium cations and compositions containing these cations are also described. Ionic compositions, particularly liquid ionic compositions that contain the aminopyridinium cation or piperidino pyridinium cation are also described. Methods of enhancing the thermal stability of a compound, particularly an ionic compound, using the aminopyridinium or piperidino pyridinium cations, are also present…

    Date Issued:
    2010-03-30
    Resource Type
    Patent
  • Inventor(s):
    Allen H. Simpson, Slawomir T. Fryska, Mark L. La Forest, Roger L. Klinedinst, Alexander Mukasyan
    Patent Number:
    US 7922845 B2
    Description:

    An apparatus for bonding a first carbon composite to a second carbon composite through a reactant layer includes a housing, and a pair of conductive press plates electrically isolated from the housing. The press plates are adapted to position the two parts to be bonded with a reactant layer therebetween. The press plates are subjected to an electrical potential and a clamping force, sufficient to initiate a combustion reaction that creates a molten ceramic to bond together the carbon-carbon c…

    Date Issued:
    2011-04-12
    Resource Type
    Patent
  • Inventor(s):
    Eduardo E. Wolf
    Patent Number:
    US 7659227 B2
    Description:

    Embodiments of the present invention provide catalysts for production of hydrogen from methanol. In an embodiment, a Cu/Zn catalyst may be promoted by Zr and/or Ce, in addition to, in embodiments, Pd or another noble metal. In an embodiment, a chemical composition may have a Cu/Zn base catalyst with a promoter element of Ce, Zr, and/or Pd or another noble metal. Methods of producing hydrogen using such catalysts are also provided.

    Date Issued:
    2010-02-09
    Resource Type
    Patent
  • Inventor(s):
    Joan F. Brennecke, Edward J. Maginn
    Patent Number:
    US 6579343 B2
    Description:

    The present invention provides a method for purifying a gas by contacting the gas with a liquid ionic compound. Natural gas may be purified, removing water and carbon dioxide, by contacting the natural gas with a liquid ionic compound.

    Date Issued:
    2003-06-17
    Resource Type
    Patent
  • Inventor(s):
    Hsueh-Chia Chang, David T. Leighton
    Patent Number:
    US 6428754 B2
    Description:

    An exhaust gas treatment system and method for treating the exhaust gas of an internal combustion engine includes a catalytic converter and a catalytic preheater or igniter upstream of the catalytic converter. A bypass passage extends around the igniter such that during the ignition period about two-thirds of the exhaust gas is bypassed around the igniter and one-third passes through the igniter. The igniter raises the temperature of the exhaust gases passing therethrough to an adiabatic temp…

    Date Issued:
    2002-08-06
    Resource Type
    Patent
  • Inventor(s):
    Eduardo E. Wolf, Paul McAllister
    Patent Number:
    US 5312679 B2
    Description:

    A catalytic carbon formation technique in a carbon fiber substrate is disclosed. The carbon fiber substrate is first impregnated with a catalyst and is thereafter heated in an atmosphere rich in carbon and hydrogen. The catalyst is typically a Group VIII metal and may be selected from the group consisting of iron, nickel and cobalt. An incipient wetness technique for impregnating the substrate is also disclosed. A salt of the catalyst is provided in solution and void volume of the substrate i…

    Date Issued:
    1994-05-17
    Resource Type
    Patent
  • Inventor(s):
    James J. Carberry, Charles Benjamin Alcock
    Patent Number:
    US 5286698 B2
    Description:

    Solid oxide solutions of the formula La.sub.1-x Sr.sub.x CrO.sub.3-.differential. have been found to exhibit surprisingly high specific activity as catalysts for oxidation and hydrogenation reactions. The oxide solutions can be utilized in particulate form or applied as films to the surfaces of refractory substrates. The oxide solution catalysts are expected to be a viable alternative to the noble metal catalysts now used commercially for treatment of combustion chamber exhaust gases to reduc…

    Date Issued:
    1994-02-15
    Resource Type
    Patent
  • Inventor(s):
    Paul J. McGinn, Hongmei An
    Patent Number:
    US 8356475 B2
    Description:

    Described is a method of slowly releasing a catalyst for, inter alia, the purpose of soot oxidation in a particulate filter. An example method includes incorporating an alkali metal oxide in a glass. Slow leaching of the alkali from the glass provides a means to gradually deliver the catalyst over extended periods. Additionally, the example method includes increasing the amount of alkaline metal ions that may be leached from the glass.

    Date Issued:
    2013-01-22
    Resource Type
    Patent
  • Inventor(s):
    Murlin T. Howerton
    Patent Number:
    US 2670393 B2
    Description:

    This invention relates to a novel method for the production of polyisobutenes, and more particularly to the catalytic polymerization of isobutene to form low molecular weight polyisobutenes.

    Date Issued:
    1954-02-23
    Resource Type
    Patent