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  • Author(s):
    Glen Niebur
    Abstract:

    Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer cells thrive in this environment could provide insight into new approaches to prevent or treat metastasis to bone. We used 4T1 cells as a model of breast cancer cells, and implanted them in gelatin hydrogels with moduli of …

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  • Author(s):
    Glen Niebur
    Abstract:

    Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer cells thrive in this environment could provide insight into new approaches to prevent or treat metastasis to bone. We used 4T1 cells as a model of breast cancer cells, and implanted them in gelatin hydrogels with moduli of …

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  • Creator(s):
    Marc Muller, Jaynise Perez-Valentin
    Description:

    This dataset accompanies the Manuscript “Impact of Hurricane Maria on beach erosion in Puerto Rico: remote sensing and causal inference” by Jaynise Perez-Valentin and Marc F. Muller, November 2019.

    beachesGIS is a zip archive that contains GIS vectors of 75 beach polygons across Puerto Rico. The vectors are provided in ESRI Shapefile format and LatLong coordinate system and have an attribute table with a beach name.

    TimeSeries is a csv table containing time series of shoreline pos…

    Date Created:
    2019-11-06
    Record Visibility:
    Public
  • Author(s):
    Peter M. Kogge
    Abstract:

    The last decade has seen the growth of data sets that are not only extremely large, but also often unstructured and very dynamic, with the desire to extract not just specific facts about specific entities but also relationships between possibly arbitrary entities. Graphs have emerged as a valuable and productive paradigm for expressing such problems, and there has been an explosion in new graph algorithms, graph query languages, and graph engines that perform such computations. However, given…

    Date Created:
    2019-09-10
    Record Visibility:
    Public
    Resource Type
    Report
  • Creator(s):
    Glen L. Niebur, Kimberly J. Curtis
    Description:

    Segmented computed tomography images of bone samples in Scanco AIM format (read with ImageJ): xxxx_seg.aim VTK format images of CFD results showing shear stress in the marrow (variable s0) (read with Python or other VTK compatible software): xxxxx.vtk Excel spreadsheet with gene expression data: xxx.xlsx

    Date Created:
    2019-04-24
    Record Visibility:
    Public
  • Creator(s):
    David H Richter, Anne E Dempsey
    Description:

    Data for the reproduction of figures found in the paper Turbulent transport of spray droplets in the vicinity of moving surface waves written by David Richter et al.

    Included in this data set is: Spray Droplet Concentration, normalized velocity, and surf. Joint probability distributions of the droplet ejection location with (a) the droplet death location, (b) the maximum height reached by the droplet during its lifetime, and © the droplet lifetime for Cases d10 and d100.

    Date Created:
    2019-03-29
    Record Visibility:
    Public
  • Creator(s):
    Kenneth Christensen, Nathaniel R. Bristow
    Date Created:
    2019-03-19
    Record Visibility:
    Public
  • Author(s):
    Yide Zhang, Scott S. Howard, Cody J. Smith
    Abstract:

    Super-resolution microscopy is broadening our in-depth understanding of cellular structure. However, super-resolution approaches are limited, for numerous reasons, from utilization in longer-term intravital imaging. We devised a combinatorial imaging technique that combines deconvolution with stepwise optical saturation microscopy (DeSOS) to circumvent this issue and image cells in their native physiological environment. Other than a traditional confocal or two-photon microscope, this approac…

    Date Created:
    2019-01-09
    Record Visibility:
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    Resource Type
    Software
  • Author(s):
    Jeremy Fein, Clayton Johnson, Joshua Shrout
    Abstract:

    Understanding metal sorption to bacteria is important for developing bioremediation strategies, for determining the fate of contaminants in ground water systems, and for defining controls on microbial metabolic processes in the environment. X-ray absorption spectroscopy (XAS) has been the only technique available for quantifying and mapping metal sorption to bacteria on an individual cell scale, but the XAS approach is time consuming and expensive, and quantitative mapping of the distribution…

    Date Published:
    2018-04
    Record Visibility:
    Public
  • Author(s):
    Jakub Plášil, Anthony R. Kampf, Peter C. Burns
    Abstract:

    Redcanyonite (IMA2016-082), (NH4)2Mn(UO2)4O4(SO4)24, occursunderground in the Blue Lizard mine, Red Canyon, White Canyon district,San Juan County, Utah, USA. It occurs with natrozippeite, brochantite, devilline, posnjakite, johannite, gypsum, bobcookite, pickingerite, pentahydrite, and the NH4-analog of zippeite, ammoniozippeite. Redcanyonite occurs as radial aggregates of red-orange needles and blades individually reaching up to 0.2 mm in length, with aggregates measuring up to 1 mm i…

    Date Published:
    2018-05
    Record Visibility:
    Public
  • Author(s):
    Bradley Ellis, Aylin Acun, U. Isik Can, Pinar Zorlutuna
    Abstract:

    The heart wall tissue, or the myocardium, is one of the main targets in cardiovascular disease prevention and treatment. Animal models have not been sufficient in mimicking the human myocardium as evident by the very low clinical translation rates of cardiovascular drugs. Additionally, current in vitro models of the human myocardium possess several shortcomings such as lack of physiologically relevant co-culture of myocardial cells, lack of a 3D biomimetic environment, and the use of non-huma…

    Date Published:
    2017-03
    Record Visibility:
    Public
  • Author(s):
    Genevieve D. Vigil, Lina Cao, Aamir A. Khan, David Benirschke, Tahsin Ahmed, Patrick Fay, Scott S. Howard
    Abstract:

    Fluorophore saturation is the key factor limiting the speed and excitation range of fluorescence lifetime imaging microscopy (FLIM). For example, fluorophore saturation causes incorrect lifetime measurements when using conventional frequency-domain FLIM at high excitation powers. In this Letter, we present an analytical theoretical description of this error and present a method for compensating for this error in order to extract correct lifetime measurements in the limit of fluorophore satura…

    Date Published:
    2016-12
    Record Visibility:
    Public