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  • Author(s):
    Bruno Garcia Silva, Patricia Perez-Calleja, Eugenio Foresti, Robert Nerenberg
    Abstract:

    The foam-aerated biofilm reactor (FABR) is a novel biofilm process that can simultaneously remove carbon and nitrogen from wastewater. A porous polyurethane foam sheet forms an interface between wastewater and aerated water, making it a counter-diffusional biofilm process similar to the membrane-aerated biofilm reactor (MABR). However, it is not clear how biofilm develops the foam interior, and how this impacts mass transfer and performance. This research explored biofilm development within t…

    Date Published:
    2022-04
    Record Visibility:
    Public
  • Author(s):
    Varun Mannam
    Abstract:

    Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique in biomedical research that uses the fluorophore decay rate to provide additional contrast in fluorescence microscopy. However, at present, the calculation, analysis, and interpretation of FLIM is a complex, slow, and computationally expensive process. Machine learning (ML) techniques are well suited to extract and interpret measurements from multi-dimensional FLIM data sets with substantial improvement in speed over conv…

    Date Published:
    2020-09
    Record Visibility:
    Public
  • Author(s):
    Eduardo Fernando Mello, Peter Bauer
    Abstract:

    http://www.energy-proceedings.org/on-energy-optimal-speed-trajectories-in-urban-traffic-implementation-options/

    Realization methods for energy optimal urban driving are the prime focus of this paper. Insights into the real-time generation of such trajectories as well as “in traffic” methods for their execution are provided. This includes the usage of piecewise linear approximations of typical urban speed profiles, urban platooning, filtering of trajectories, and modifying initial acceleratio…

    Date Published:
    2020
    Record Visibility:
    Public
  • Author(s):
    Nada Salem Alakhras, Jaeho Shin, Scott S. Smith, Basar Bilgicer, Mark H. Kaplan
    Abstract:

    Link to this article: https://www.jimmunol.org/content/204/1_Supplement/66.9

    Anaphylaxis to peanut allergen is a severe hypersensitive allergic reaction characterized by life-threatening symptoms. Anaphylaxis is mediated by IgE-dependent mast cell activation that leads to the release of inflammatory mediators. In a previous report, we described the design of a covalent heterobivalent inhibitor (cHBI) that selectively forms covalent bonds with allergen specific-IgE (sIgE) on mast cells and ab…

    Date Published:
    2020-05
    Record Visibility:
    Public
  • Author(s):
    Shikang Liu, David Hachen, Omar Lizardo, Christian Poellabauer, Aaron Striegel, Tijana Milenković
    Abstract:

    Free PMC Article located at: https://pubmed.ncbi.nlm.nih.gov/31797634/

    Precision medicine has received attention both in and outside the clinic. We focus on the latter, by exploiting the relationship between individuals’ social interactions and their mental health to predict one’s likelihood of being depressed or anxious from rich dynamic social network data. Existing studies differ from our work in at least one aspect: they do not model social interaction data as a network; they do …

    Date Published:
    2020
    Record Visibility:
    Public
  • Author(s):
    Christianos Burlotos
    Abstract:

    The residential construction industry in developing nations is often plagued by numerous constraining systems, including underdeveloped financial markets, ineffective governing bodies, and unregulated material and labor markets, which restrict safe and disaster-resilient housing to the wealthy minority. The majority are left in nonengineered, informally constructed homes, which, in countries with high exposure to hydro-meteorological and/or seismic hazards, can prove deadly. The thesis presen…

    Date Created:
    2020-08-25
    Record Visibility:
    Public
  • Author(s):
    Ankit Agrawal, Seyedehzahra Khoshmanesh, Michael Vierhauser, Mona Rahimi, Jane Cleland-Huang, Robyn Lutz
    Abstract:

    Safety Assurance Cases (SACs) are increasingly used to guide and evaluate the safety of software-intensive systems. They are used to construct a hierarchically organized set of claims, arguments, and evidence in order to provide a structured argument that a system is safe for use. However, as the system evolves and grows in size, a SAC can be difficult to maintain. In this paper we utilize design science to develop a novel solution for identifying areas of a SAC that are affected by changes t…

    Date Published:
    2019-05
    Record Visibility:
    Public
  • Author(s):
    Rick Rabiser, Klaus Schmid, Holger Eichelberger, Michael Vierhauser, Sam Guinea, Paul Gruenbacher
    Abstract:

    [Context] Complex and heterogeneous software systems need to be monitored as their full behavior often only emerges at runtime, e.g., when interacting with other systems or the environment. Software monitoring approaches observe and check properties or quality attributes of software systems during operation. Such approaches have been developed in diverse communities for various kinds of systems and purposes. For instance, requirements monitoring aims to check at runtime whether a software…

    Date Created:
    2019-05-06
    Record Visibility:
    Public
  • Author(s):
    Michael Vierhauser, Sean Beyley, Jane Wyngaard, Wandi Xiong, Joshua Huseman, Robyn Lutz, Jane Cleland-Huang
    Abstract:

    The growing adoption of unmanned aerial vehicles (UAV) for tasks such as eCommerce, aerial surveillance, and environmental monitoring introduces the need for new safety mechanisms in an increasingly cluttered airspace. In our work we thus emphasize safety issues that emerge at the intersection of infrastructures responsible for controlling the airspace, and the diverse UAVs operating in their space. We build on safety assurance cases (SAC)- a state-of-the-art solution for reasoning about safe…

    Date Created:
    2019-05-06
    Record Visibility:
    Public
  • Author(s):
    Norbert Seyff, Michael Vierhauser, Michael Schneider, Jane Cleland-Huang
    Abstract:

    [Context and motivation] With the rise of cyber-physical systems (CPS), smart ecosystems, and the Internet of Things (IoT), software-intensive systems have become pervasive in everyone’s daily life. The shift from software systems to ubiquitous adaptive software-intensive systems not only affects the way we use software but further has an impact on the way these systems are designed and developed. Gathering requirements for such systems can benefit from elicitation processes that are conducte…

    Date Created:
    2019-05-06
    Record Visibility:
    Public
  • Author(s):
    Jane Cleland-Huang, Michael Vierhauser
    Abstract:

    Traditionally, safety-critical projects have been developed using the waterfall process. However, this makes it costly and challenging to incrementally introduce new features and to certify the modified product for use. As a result, there has been increasing interest in adopting agile development paradigms within the safety-critical domain. This in turn introduces numerous challenges. In this paper we address the specific problems of discovering, analyzing, specifying, and managing safety req…

    Date Published:
    2018-08
    Record Visibility:
    Public
  • Author(s):
    Michael Vierhauser, Jane Cleland-Huang, Rick Rabiser, Thomas Krismayer, Paul Grünbacher
    Abstract:

    Industrial software systems are often systems of systems~(SoS) whose full behavior only emerges during operation. They therefore require monitoring techniques to observe systems and detect deviations from their requirements. The focus of existing monitoring approaches, however, is mainly on detecting violations of expected behavior, while support for diagnosing violations is typically limited or even neglected. Diagnosis is particularly challenging in SoS due to their technological heterogene…

    Date Published:
    2018-08
    Record Visibility:
    Public