College of Engineering

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  • Author(s):
    Glen Niebur
    Abstract:

    Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer cells thrive in this environment could provide insight into new approaches to prevent or treat metastasis to bone. We used 4T1 cells as a model of breast cancer cells, and implanted them in gelatin hydrogels with moduli of …

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  • Author(s):
    Glen Niebur
    Abstract:

    Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer cells thrive in this environment could provide insight into new approaches to prevent or treat metastasis to bone. We used 4T1 cells as a model of breast cancer cells, and implanted them in gelatin hydrogels with moduli of …

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  • Creator(s):
    Varun Mannam
    Description:

    We created a small dataset to validate the lifetime denoising using the trained Noise2Noise-NBN model - the Fluorescence Microscopy Lifetime Denoising (FMLD) dataset - that is dedicated to perform the lifetime denoising from the noisy (raw) lifetime images.

    The dataset consists of 50 real fluorescence microscopy images obtained with custom-built two-photon microscope and representative fixed BPAE cell (F36924) samples. We use all 50 images for testing/inference. These images are captured wi…

    Date Created:
    2020-01-01
    Record Visibility:
    Public
  • Creator(s):
    Varun Mannam
    Description:

    We created a dataset - the Lifetime From Intensity (LFI) dataset - that is dedicated to estimate the lifetime from intensity images. The dataset consists of 156 real fluorescence microscopy images obtained with custom-built two-photon microscope and representative biological zebrafish samples. We use 140 images for training and 16 images for testing. These images are captured with 2 different excitation wavelengths (800 and 920 nm) and different power levels (5 mW and 8 mW).

    Date Created:
    2019-08-13
    Record Visibility:
    Public
  • Author(s):
    Christianos Burlotos
    Abstract:

    The residential construction industry in developing nations is often plagued by numerous constraining systems, including underdeveloped financial markets, ineffective governing bodies, and unregulated material and labor markets, which restrict safe and disaster-resilient housing to the wealthy minority. The majority are left in nonengineered, informally constructed homes, which, in countries with high exposure to hydro-meteorological and/or seismic hazards, can prove deadly. The thesis presen…

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  • Author:
    Pingjie Tang
    Advisory Committee:
    Nitesh V. Chawla
    Degree Area:
    Computer Science and Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-07-30
    Record Visibility:
    Public
  • Author:
    Matthew J. Filmer
    Advisory Committee:
    Anthony Hoffman, Gregory L. Snider, Craig Lent, Alexei O. Orlov, Patrick Fay
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-07-13
    Record Visibility:
    Public
  • Author:
    Alireza Partovi
    Advisory Committee:
    Lin Hai
    Degree Area:
    Electrical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-07-15
    Record Visibility:
    Public
  • Author:
    Steven L. Claucherty
    Advisory Committee:
    Thomas Juliano, Katya Casper, Flint Thomas, Hirotaka Sakaue
    Degree Area:
    Aerospace and Mechanical Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-07-13
    Record Visibility:
    Public
  • Author:
    Daniel (Yue) Zhang
    Advisory Committee:
    Dong Wang
    Degree Area:
    Computer Science and Engineering
    Degree:
    Doctor of Philosophy
    Defense Date:
    2020-05-13
    Record Visibility:
    Public
  • Creator(s):
    Christianos Burlotos
    Description:

    This multilayered spreadsheet is used to assist aspiring homeowners design their home from a pre-set list of options for floorplans, finishes, fixtures, and basic services. It also rapidly calculates an estimated total cost for the structure as well as a corresponding monthly payment amount. This allows the design process to be performed iteratively, giving families autonomy in the design of their own home, the chance to consider a variety of options and combinations, and the immediate knowle…

    Date Created:
    2020-07-20
    Record Visibility:
    Public
  • Creator(s):
    Christianos Burlotos
    Description:

    This tool calculates the design loads on a reinforced concrete special moment frame with a concrete slab roof, determines force and moment demands through an approximate portal frame analysis, assesses load combinations, evaluates the capacity of members compared to the demands, and approximates the cost of needed construction materials. It was produced by MSCE student Christianos Burlotos in order to parametrically assess frames to determine the best-fit frame for single-family homes in Leog…

    Date Created:
    2020-07-20
    Record Visibility:
    Public