College of Engineering

Search CurateND

Search criteria:

Department or Unit: College of Engineering remove × Type of Work: Software OR Article OR Patent OR Dataset OR Master's Thesis remove ×
Clear all

List of files deposited in CurateND that match your search criteria

  • Author(s):
    Jane Cleland-Huang, Michael Vierhauser
    Abstract:

    Traditionally, safety-critical projects have been developed using the waterfall process. However, this makes it costly and challenging to incrementally introduce new features and to certify the modified product for use. As a result, there has been increasing interest in adopting agile development paradigms within the safety-critical domain. This in turn introduces numerous challenges. In this paper we address the specific problems of discovering, analyzing, specifying, and managing safety req…

    Date Published:
    2018-08
    Record Visibility:
    Public
  • Author(s):
    Yide Zhang, Scott S. Howard, Cody J. Smith
    Abstract:

    Super-resolution microscopy is broadening our in-depth understanding of cellular structure. However, super-resolution approaches are limited, for numerous reasons, from utilization in longer-term intravital imaging. We devised a combinatorial imaging technique that combines deconvolution with stepwise optical saturation microscopy (DeSOS) to circumvent this issue and image cells in their native physiological environment. Other than a traditional confocal or two-photon microscope, this approac…

    Date Created:
    2019-01-09
    Record Visibility:
    Public
    Resource Type
    Software
  • Author(s):
    Michael Vierhauser, Jane Cleland-Huang, Rick Rabiser, Thomas Krismayer, Paul Grünbacher
    Abstract:

    Industrial software systems are often systems of systems~(SoS) whose full behavior only emerges during operation. They therefore require monitoring techniques to observe systems and detect deviations from their requirements. The focus of existing monitoring approaches, however, is mainly on detecting violations of expected behavior, while support for diagnosing violations is typically limited or even neglected. Diagnosis is particularly challenging in SoS due to their technological heterogene…

    Date Published:
    2018-08
    Record Visibility:
    Public
  • Author:
    Stefanie R Lewis
    Advisory Committee:
    Peter C. Burns, Clive R. Neal, Antonio Simonetti
    Degree Area:
    Civil and Environmental Engineering and Earth Sciences
    Degree:
    Master of Science in Earth Sciences
    Defense Date:
    2018-09-24
    Record Visibility:
    Public
  • Author(s):
    Kyle Sweeney, Douglas Thain
    Abstract:

    Scientists using workflows often have access to both High Performance Computing and High-Throughput Computing sites, but HPC sites’ architecture is less conducive to HTC paradigms. The choices of middleware and site can have drastic performance differences on different workflows. To explore these differences, we created tools to expand Makeflow and Work Queue’s capabilities. We then performed four speed of light tests, testing job dispatch rate, data delivery from the master to worker…

    Record Visibility:
    Public
  • Author(s):
    Jeremy Fein, Clayton Johnson, Joshua Shrout
    Abstract:

    Understanding metal sorption to bacteria is important for developing bioremediation strategies, for determining the fate of contaminants in ground water systems, and for defining controls on microbial metabolic processes in the environment. X-ray absorption spectroscopy (XAS) has been the only technique available for quantifying and mapping metal sorption to bacteria on an individual cell scale, but the XAS approach is time consuming and expensive, and quantitative mapping of the distribution…

    Date Published:
    2018-04
    Record Visibility:
    Public
  • Author(s):
    Jakub Plášil, Anthony R. Kampf, Peter C. Burns
    Abstract:

    Redcanyonite (IMA2016-082), (NH4)2Mn(UO2)4O4(SO4)24, occursunderground in the Blue Lizard mine, Red Canyon, White Canyon district,San Juan County, Utah, USA. It occurs with natrozippeite, brochantite, devilline, posnjakite, johannite, gypsum, bobcookite, pickingerite, pentahydrite, and the NH4-analog of zippeite, ammoniozippeite. Redcanyonite occurs as radial aggregates of red-orange needles and blades individually reaching up to 0.2 mm in length, with aggregates measuring up to 1 mm i…

    Date Published:
    2018-05
    Record Visibility:
    Public
  • Author(s):
    Bradley Ellis, Aylin Acun, U. Isik Can, Pinar Zorlutuna
    Abstract:

    The heart wall tissue, or the myocardium, is one of the main targets in cardiovascular disease prevention and treatment. Animal models have not been sufficient in mimicking the human myocardium as evident by the very low clinical translation rates of cardiovascular drugs. Additionally, current in vitro models of the human myocardium possess several shortcomings such as lack of physiologically relevant co-culture of myocardial cells, lack of a 3D biomimetic environment, and the use of non-huma…

    Date Published:
    2017-03
    Record Visibility:
    Public
  • Author(s):
    Genevieve D. Vigil, Lina Cao, Aamir A. Khan, David Benirschke, Tahsin Ahmed, Patrick Fay, Scott S. Howard
    Abstract:

    Fluorophore saturation is the key factor limiting the speed and excitation range of fluorescence lifetime imaging microscopy (FLIM). For example, fluorophore saturation causes incorrect lifetime measurements when using conventional frequency-domain FLIM at high excitation powers. In this Letter, we present an analytical theoretical description of this error and present a method for compensating for this error in order to extract correct lifetime measurements in the limit of fluorophore satura…

    Date Published:
    2016-12
    Record Visibility:
    Public
  • Author(s):
    Shirou Lou, Jarrod Schiffbauer, Tengfei Lou
    Abstract:

    In this work, the droplet size in a water-in-oil emulsion obtained by supersaturation is studied. The emulsion is obtained by cooling down a saturated water/oil solution by a certain temperature difference. The effects of the cooling rate and temperature difference on the produced droplet size are experimentally investigated. The average size of water droplets in the emulsion is found to be proportional to the square root of the cooling rate. By analyzing the time scales of three different st…

    Date Published:
    2017-10
    Record Visibility:
    Public
  • Author(s):
    Yide Zhang, Prakash Nallathamby, Genevieve D. Vigil, Aamir A. Khan, Devon E. Mason, Joel D. Boerckel, Ryan K. Roeder, Scott S. Howard
    Abstract:

    Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the super-resolution microscopy is not feasible in many applications. In this paper, we propose and demonstrate a saturation-based super-resolution fluorescence microscopy technique that can be easily implemented and requires neither additional hardware nor complex post-processin…

    Date Published:
    2018-04
    Record Visibility:
    Public
  • Author(s):
    Pavel A. Brodkiy, Qinfeng Wu, Francisco J. Huizar, Dharsan K. Soundarrajan, Cody Narciso, Megan evis, Ninfamaria Arredondo-Walsh, Jianxu Chen, Peixian Liang, Danny Z. Chen, Jeremiah James Zartman
    Abstract:

    Organ development is driven by a set of patterned inductive signals. However, how these signals are integrated to coordinate tissue patterning is still poorly understood. Calcium ions (Ca2+) are critical signaling components involved in signal integration and are regulated by a core Ca2+ signaling toolkit. Ca2+ signaling encodes a significant fraction of information in cells through both amplitude and frequency-dependent regulation of transcription factors and key regulatory enzymes. A range …

    Date Published:
    2017-09
    Record Visibility:
    Public