Biological Sciences

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  • Inventor(s):
    Siyuan Zhang, Jeremiah Zartman, David Hoelzle, Cody Narciso
    Patent Number:
    US 9975121 B2
    Description:

    A microfluidic device for evaluating a tissue sample can include a tissue chamber, a liquid inlet channel, a liquid outlet channel, and at least one of components (1)-(3). The tissue chamber can be defined by a plurality of walls, at least one of which is transparent. The liquid inlet and outlet channels can be in fluid communication with the tissue chamber. Components (1)-(3) can include: (1) a deformable membrane disposed within the tissue chamber and being configured to oscillate, upon app…

    Date Issued:
    2018-05-22
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Jeremiah Zartman, David Hoelzle, Cody Narciso, Siyuan Zhang, Wendy Alvarez Barrios, Victoria Zellmer
    Patent Number:
    US 10168259 B2
    Description:

    One aspect of the present disclosure can include a microfluidic device for imaging a tissue sample. The device can include a tissue chamber, a liquid inlet channel, and a liquid outlet channel. The tissue chamber can be defined by a plurality of walls, at least one of which is transparent. The liquid inlet channel can be fluid communication with the tissue chamber. The liquid outlet channel can be in fluid communication with the tissue chamber. The tissue chamber can be sized and dimensioned …

    Date Issued:
    2019-01-01
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Xu Li, Malcolm J. Fraser
    Patent Number:
    US 10087463 B2
    Description:

    The present invention provides a method for transforming an insect genome that has a much enhanced transformation frequency. The vectors and plasmids employed in the method are further described as transposition vectors that include a minimal amount of nucleotide sequence homologous to a 5’ region and a 3’ region of a native piggyBac nucleic acid sequence. The transformed cells or embryos may also be developed into transgenic organisms. Disclosed are minimal piggyBac-based plasmid con…

    Date Issued:
    2018-10-02
    Record Visibility:
    Public
    Resource Type
    Patent