Chemistry and Biochemistry

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  Patent

  Histone deacetylase inhibitors as therapeutic agents for Niemann-Pick type C disease
  

  Inventor(s):

  Olaf G. Wiest, Paul Helquist, Frederick R. Maxfield

  Patent Number:

  US 9333222 B2

  Description:

  Embodiments herein relate to the field of lysosomal storage disorders, and, more specifically, to methods of treating lysosomal storage disorders such as Niemann-Pick type C disease, for instance with inhibitors of histone deacetylases, particularly inhibitors of class 1 histone deacetylases. In various embodiments, methods of treating Niemann-Pick type C disease with inhibitors of class 1 histone deacetylases are described.

  Date Issued:

  May 10, 2016

  Record Visibility:

  Public

  Title

  Histone deacetylase inhibitors as therapeutic agents for Niemann-Pick type C disease

  Description

  Embodiments herein relate to the field of lysosomal storage disorders, and, more specifically, to methods of treating lysosomal storage disorders such as Niemann-Pick type C disease, for instance with inhibitors of histone deacetylases, particularly inhibitors of class 1 histone deacetylases. In various embodiments, methods of treating Niemann-Pick type C disease with inhibitors of class 1 histone deacetylases are described.

  Creator

  Olaf G. Wiest, Paul Helquist, Frederick R. Maxfield

  Publisher

  United States Patent and Trademark Office

  Language

  English

  Rights

  All rights reserved

  Resource Type

  Patent