College of Science

Search CurateND

Search criteria:

Department or Unit: College of Science remove ×
Clear all

List of files deposited in CurateND that match your search criteria

  • Inventor(s):
    Marvin J. Miller, Cheng Ji, Patricia A. Miller
    Patent Number:
    US 9302012 B2

    An artificial tris-catecolate siderophore with a tripodal backbone and its conjugates with ampicillin and amoxicillin were synthesized. Both conjugates exhibited significantly enhanced in vitro antibacterial activities against Gram-negative species compared to the parent drugs, especially against P. aeruginosa. The conjugates appear to be assimilated by an induced bacterial iron transport process as their activities were inversely related to iron concentration. The easily synthesized tris-cat…

    Date Issued:
    Record Visibility:
    Resource Type