College of Science

Search CurateND

Search criteria:

Department or Unit: College of Science remove × Type of Work: Patent OR Article remove ×
Clear all

List of files deposited in CurateND that match your search criteria

  • Author(s):
    Li Li, Yong Cheng, Scott Emrich, Jeffrey Schorey
    Abstract:

    Endothelial cells play an essential role in regulating an immune response through promoting leukocyte adhesion and cell migration and production of cytokines such as TNFα. Regulation of endothelial cell immune function is tightly regulated and recent studies suggest that extracellular vesicles (EVs) are prominently involved in this process. However, the importance of EVs in regulating endothelial activation in the context of a bacterial infection is poorly understood. To begin addressing this…

    Date Published:
    2018-05
  • Author(s):
    Li Li, Yong Cheng
    Abstract:

    Endothelial cells play an essential role in regulating an immune response through promoting leukocyte adhesion and cell migration and production of cytokines such as TNFα. Regulation of endothelial cell immune function is tightly regulated and recent studies suggest that extracellular vesicles (EVs) are prominently involved in this process. However, the importance of EVs in regulating endothelial activation in the context of a bacterial infection is poorly understood. To begin addressing this…

    Date Published:
    2018-05
  • Author(s):
    Paul T. Kroeger, Bridgette E. Drumond, Rachel Miceli, Michael McKernan, Gary F. Gerlach, Amanda N. Marra, Annemarie Fox, Kristen K. McCampbell, Ignaty Leshchiner, Adriana Rodriguez-Mari, Ruth Bremiller, Ryan Thummel, Alan J. Davidson, John Postlethwait, Wolfram Goessling, Rebecca Wingert
    Abstract:

    The zebrafish kidney is conserved with other vertebrates, making it an excellent genetic model to study renal development. The kidney collects metabolic waste using a blood filter with specialized epithelial cells known as podocytes. Podocyte formation is poorly understood but relevant to many kidney diseases, as podocyte injury leads to progressive scarring and organ failure. zeppelin (zep) was isolated in a forward screen for kidney mutants and identified as a homozygous recessive lethal al…

    Date Published:
    2017
  • Author(s):
    Scott Shaw, Wenqi Liu, Cesar Fernando Azael Gomez Duran, Cynthia Schreiber, Maria de Lourdes Betancourt Mendiola, Canjai Zhai, Felicia Roland, Simon Padanilam, Bradley Smith
    Abstract:

    New fluorescent molecular probes, which can selectively target specific cell surface receptors, are needed for microscopy, in vivo imaging, and image guided surgery. The preparation of multivalent probes using standard synthetic chemistry can be a laborious process due to low reaction yields caused by steric effects. In this study, fluorescent molecular probes were prepared by a programmed non‐covalent pre‐assembly process that used a near‐infrared fluorescent squaraine dye to thread a macroc…

    Date Published:
    2018
  • Author(s):
    Rene De Vogelaere
    Abstract:

    Hamilton equations are such that the relation, between the coordinates and momenta at time t and at time t 0, is a contact transformation. Methods of integration of Hamilton equations, which do preserve the contact transformation property are given here. These methods are of first and second order. They are given, for the equation x= f(x,t), then for the case of one degree of freedom, then for the general case. Some of the formulae are implicit.

    Date Published:
    1956-04
  • 18

    Article

    Author(s):
    Daniel Bates, Andrew Sommese, Jonathan Hauenstein
    Abstract:

    Numerical algebraic geometry is the area devoted to the solution and manipulation of polynomial systems by numerical methods, which are mainly based on continuation. Due to the extreme intrinsic parallelism of continuation, polynomial systems may be successfully dealt with that are much larger than is possible with other methods. Singular solutions require special numerical methods called endgames, and the endgames currently used do not take advantage of parallelism. This article gives an ove…

  • Author(s):
    Charles Wampler II, Daniel Bates, Andrew Sommese, Jonathan Hauenstein
    Abstract:

    Dedicated to our collaborator, mentor, and friend, Andrew Sommese, by Bates, Hauenstein, and Wampler on the occasion of his sixtieth birthday.

    When numerically tracking implicitly-defined paths, such as is required for homotopy continuation methods, efficiency and reliability are enhanced by using adaptive stepsize and adaptive multiprecision methods. Both efficiency and reliability can be further improved by adapting precision and stepsize simultaneously. This paper presents a strategy fo…

  • Author(s):
    Charles Wampler, Andrew Sommese, Jonathan Hauenstein
    Abstract:

    Though numerical methods to find all the isolated solutions of nonlinear systems of multivariate polynomials go back 30 years, it is only over the last decade that numerical methods have been devised for the computation and manipulation of algebraic sets coming from polynomial systems over the complex numbers. Collectively, these algorithms and the underlying theory have come to be known as numerical algebraic geometry. Several software packages are capable of carrying out some of the operati…

  • Author(s):
    Daniel Bates, Andrew Sommese, Jonathan Hauenstein
    Abstract:

    Path tracking is the fundamental computational tool in homotopy continuation and is therefore key in most algorithms in the emerging field of numerical algebraic geometry. Though the basic notions of predictor-corrector methods have been known for years, there is still much to be considered, particularly in the specialized algebraic setting of solving polynomial systems. In this article, the effects of the choice of predictor method on the performance of a tracker is analyzed, and details for…

  • Author(s):
    Andrew Sommese, Azat M. Gainutdinov, Wenrui Hao, Rafael I. Nepomechie
    Abstract:

    We consider the sl(2)q-invariant open spin-½ XXZ quantum spin chain of finite length N. For the case that q is a root of unity, we propose a formula for the number of admissible solutions of the Bethe ansatz equations in terms of dimensions of irreducible representations of the Temperley-Lieb algebra; and a formula for the degeneracies of the transfer matrix eigenvalues in terms of dimensions of tilting sl(2)q-modules. These formulas include corrections that appear if two or more tilting …

  • Author(s):
    Michael Wiescher, de Boer, R.J. , Bardayan, D.W., Go¨rres, J.
    Abstract:

    Background: The slowest reaction in the first CNO cycle is 14N(p,γ ) 15O, therefore its rate determines the overall energy production efficiency of the entire cycle. The cross section presents several strong resonance contributions, especially for the ground-state transition. Some of the properties of the corresponding levels in the 15O compound nucleus remain uncertain, which affects the uncertainty in extrapolating the capture cross section to the low energy range of astrophysical interest….

  • Author(s):
    David Severson, Anastasia N. Naumenko, Vladimir A. Timoshevskiy, Nicholas A. Kinney, Alina A. Kokhanenko, Becky S. deBruyn, Diane D. Lovin, Vladimir N. Stegniy, Igor V. Sharakhov, Maria V. Sharakhova
    Abstract:

    The genome assembly of southern house mosquito Cx. quinquefasciatus is represented by a high number of supercontigs with no order or orientation on the chromosomes. Although cytogenetic maps for the polytene chromosomes of this mosquito have been developed, their utilization for the genome mapping remains difficult because of the low number of high-quality spreads in chromosome preparations. Therefore, a simple and robust mitotic-chromosome-based approach for the genome mapping of Cx. quinque…