Center for Nano Science and Technology (NDnano)

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  Article

  Super-resolution fluorescence microscopy by stepwise optical saturation
  

  Author(s):

  Yide Zhang, Prakash Nallathamby, Genevieve D. Vigil, Aamir A. Khan, Devon E. Mason, Joel D. Boerckel, Ryan K. Roeder, Scott S. Howard

  Abstract:

  Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the super-resolution microscopy is not feasible in many applications. In this paper, we propose and demonstrate a saturation-based super-resolution fluorescence microscopy technique that can be easily implemented and requires neither additional hardware nor complex post-processin…

  Date Published:

  2018-04

  Record Visibility:

  Public