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  • Author(s):
    Yide Zhang, Scott S. Howard, Cody J. Smith

    Super-resolution microscopy is broadening our in-depth understanding of cellular structure. However, super-resolution approaches are limited, for numerous reasons, from utilization in longer-term intravital imaging. We devised a combinatorial imaging technique that combines deconvolution with stepwise optical saturation microscopy (DeSOS) to circumvent this issue and image cells in their native physiological environment. Other than a traditional confocal or two-photon microscope, this approac…

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  • Inventor(s):
    Christopher R. Sweet, James C. Sweet
    Patent Number:
    US 9972120 B2

    A method of mapping a two-dimensional image to a three-dimensional surface includes capturing data for a two-dimensional image and a three-dimensional structure. A process determines coincident points between the 2D image and the 3D structure and maps points on the 2D image to the 3D structure by assigning relative two-coordinate points from the two dimensional image to relative three-coordinate points of the three-dimensional structure. The mapping creates a 3D surface and texturing and remo…

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