Integrated Imaging Facility

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  • Author(s):
    Karen A. Bailey, Yuliya Klymenko, Peter E. Feist, Amanda B. Hummon, M. Sharon Stack, Zachary D. Schultz
    Abstract:

    Ovarian cancer (OvCa) cells are reported to undergo biochemical changes at the cell surface in response to treatment with lysophosphatidic acid (LPA). Here we use scanning electron microscopy (SEM) and multiplex coherent anti-Stokes Raman scattering (CARS) imaging via supercontinuum excitation to probe morphological changes that result from LPA treatment. SEM images show distinct shedding of microvilli-like features upon treatment with LPA. Analysis of multiplex CARS images can distinguish be…

    Date Published:
    2017
    Record Visibility:
    Public