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  Article

  Development of a target-free high-throughput screening platform for the discovery of antileishmanial compounds
  

  Author(s):

  Brianna Norris-Mullins, Bruce J. Melancon, Miguel A. Morales, Mary Ann McDowell

  Abstract:

  Leishmania parasites are the causative agents of a wide spectrum of human diseases. The clinical mani- festations of leishmaniasis range from self-healing skin lesions to fatality. The World Health Organization has classed leishmaniasis as a category 1 neglected tropical disease. Leishmaniasis represents a major in- ternational health challenge, affecting 12 million people per year and with nearly 310 million people at risk. The first-line chemotherapies used to treat leishmaniasis are intrav…

  Date Published:

  2019-07

  Record Visibility:

  Public