Notre Dame Research

Search CurateND

Search criteria:

Department or Unit: Notre Dame Research remove ×
Clear all

List of files deposited in CurateND that match your search criteria

  • Author(s):
    Bradley D. Smith
    Abstract:

    Macrocyclic hosts have long been used for guest encapsulation, and recently a new application has emerged; employment as supramolecular elements for capture and recovery of gold through host/guest co-precipitation. The guests are square-planar tetrahaloaurate anions, practically important gold complexes with a capacity to engage in non-covalent interactions such as hydrogen bonding and Au–! interactions. The successful macrocyclic hosts for co-precipitation include cyclodextrins, cucurbituril…

    Date Published:
    2021-01
    Record Visibility:
    Public
  • Author(s):
    Janeala J. Morsby, Madushani Dharmarwardana, Hannah McGarraugh, Bradley D. Smith
    Abstract:

    A tetralactam macrocycle acts as a novel supramolecular adjuvant to capture a released resorufin dye and create a higher contrasting yellow/blue color change for enhanced naked eye interpretation of a colorimetric indicator assay.

    Date Published:
    2020-07
    Record Visibility:
    Public
  • Author(s):
    Cynthia L. Schreiber, Canjia Zhai, Bradley D. Smith
    Abstract:

    “Targeted fluorescent molecular probes are useful for cell microscopy, diagnostics, and biological imaging. An emerging discovery paradigm is to screen libraries of fluorescent molecules and identify hit compounds with interesting targeting properties. However, a current limitation with this approach is the lack of fluorescent molecular scaffolds that can produce libraries of probe candidates with three dimen- sional globular shape, chiral centers, and constrained conformation. Th…

    Date Published:
    2021-03
    Record Visibility:
    Public
  • Author(s):
    Kirk M. Atkinson, Janeala J. Morsby, Sai Shradha Reddy Kommidi, Bradley D. Smith
    Abstract:

    Continued advancement in bioresponsive fluorescence imaging requires new classes of activatable fluorescent probes that emit near-infrared fluorescence with wavelengths above 740 nm. Heptamethine cyanine dyes (Cy7) have suitable fluorescence properties but it is challenging to create activatable probes because Cy7 dyes have a propensity for self-aggregation and fluorescence quenching. A new synthetic strategy is employed to create a generalizable class of hydrophilic bioresponsive near-infrar…

    Date Published:
    2021-03
    Record Visibility:
    Public
  • Author(s):
    Madushani Dharmarwardana, Janel M. Dempsey, Sasha Padilla-Coley, Tia S. Jarvis, Kejia Shi, Kirk M. Atkinson, Bradley D. Smith
    Abstract:

    A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and ‘‘turn on’’ visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage induced by the biomedically important enzyme phospholipase A2.

    Date Published:
    2021-06
    Record Visibility:
    Public
  • Author(s):
    Hyein Do, Seung-Ryong Kwon, Seol Baek, Chinedu S. Madukoma, Marina Smiley, Lars Dietrich, Joshua Shrout, Paul Bohn
    Abstract:

    The opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa) produces several redox-Active phenazine metabolites, including pyocyanin (PYO) and phenazine-1-carboxamide (PCN), which are electron carrier molecules that also aid in virulence. In particular, PYO is an exclusive metabolite produced by P. aeruginosa, which acts as a virulence factor in hospital-Acquired infections and is therefore a good biomarker for identifying early stage colonization by this pathogen. Here, we describe the…

    Date Published:
    2021-01
    Record Visibility:
    Public
  • Author(s):
    Paul Bohn
    Abstract:

    We present the results of acid-base experiments performed at the single ion (H+ or OH-) limit in ∼6 aL volume nanopores incorporating electrochemical zero-mode waveguides (E-ZMWs). At pH 3 each E-ZMW nanopore contains ca. 3600H+ ions, and application of a negative electrochemical potential to the gold working electrode/optical cladding layer reduces H+ to H2, thereby depleting H+ and increasing the local pH within the nanopore. The change in pH was quantified by tracking the intensity of fluo…

    Date Published:
    2020-09
    Record Visibility:
    Public
  • Author(s):
    Chao Tang, Andriy Yaroshchuk, Merlin Bruening
    Abstract:

    Flow through negatively charged nanopores separates Li+and K+with selectivities of up to 70 and Li+passages from 20% to above 100%. Remarkably, both the Li+/K+selectivity and Li+passage initially increase with flow rate, breaking the permeability/selectivity trade-off. Modelling demonstrates that flow through the membranes creates electric fields that retard transport of cations. Selectivity increases with flow rate because the K+electromigration velocity exceeds its convective velocity, but …

    Date Published:
    2020-05
    Record Visibility:
    Public
  • Author(s):
    Rui Zhao, Benjamin Grisafe, Ram Krishna Ghosh, Ke Wang, Suman Datta, Joshua Robinson
    Abstract:

    The 1T phase of tantalum disulfide (1T-TaS 2 ) possesses a variety of charge-density-wave (CDW) orders, and as a result, it attracts an increasing amount of academic and technological interest. The 1T phase of tantalum disulfide (1T-TaS 2 ) possesses a variety of charge-density-wave (CDW) orders, and as a result, it attracts an increasing amount of academic and technological interest. Researchers have devoted tremendous efforts towards understanding the impacts of doping, alloying, intercalat…

    Date Published:
    2019-04
    Record Visibility:
    Public
  • Author(s):
    Michael A. VendenBerg, Edgar Ruiz Bello, Calvin Nazareth, Matthew J. Webber
    Abstract:

    The self-assembly of oppositely charged oligopeptide mixtures is evaluated, observing self-sorting into distinct, yet still interacting, nanostructures.Significant efforts in the field of supramolecular materials have strived to co-assemble small molecules in order to realize individual nanostructures with multiple, tunable activities. The design of self-assembling motifs bearing opposite charges is one commonly used method, with favorable electrostatic interactions used to promote mixing in …

    Date Published:
    2019-08
    Record Visibility:
    Public
  • Author(s):
    R. Marks, K. Doudrick
    Abstract:

    Chlorite (ClO 2 - ) is a disinfection byproduct formed during drinking water treatment when source waters with a high oxidant demand are disinfected with chlorine dioxide. This study investigated the reduction of… Chlorite (ClO 2 - ) is a disinfection byproduct formed during drinking water treatment when source waters with a high oxidant demand are disinfected with chlorine dioxide. This study investigated the reduction of ClO 2 - using a visible light (Vis) active photocatalyst, bismuth va…

    Date Published:
    2019-08
    Record Visibility:
    Public
  • Author(s):
    Man Yang, Wei Lu, Renxi Jin, Xian-Chun Liu, Shuyan Song, Yan Xing
    Abstract:

    In this work, ZIF-67 is self-grown on the NiCo layered double hydroxide (NiCo-LDH) nanosheets-modified Ni foam (NF) surface. Its derivative, the hierarchically structured Co3O4/NiCo2O4/Ni foam (CO/NCO/NF) composite, is successfully fabricated by the oxidation of ZIF-67/NiCo-LDH/ NF, which exhibits excellent electrocatalytic performance. When assessed as an electrode for oxygen evolution reaction (OER), the CO/NCO/NF electrode shows low overpotentials of 320 and 407 mV at 10 and 50 mA cm−2, re…

    Date Published:
    2019-06
    Record Visibility:
    Public