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  • Author(s):
    A. Vania Apkarian, Kasturi Halder, Suhail Alam, Maria Virginia Centeno
    Abstract:

    The disclosure relates to use of a triple formulation comprising a histone deacytlase, a cyclodextrin and polyethylene glycol or propylene glycol, and in the treatment and management of chronic pain.

    Date Created:
    2019-10-15
    Resource Type
    Document
  • Author(s):
    Yide Zhang, Yinhao Zhu, Evan Nichols, Qingfei Wang, Siyuang Zhang, Cody Smith, Scott Howard
    Abstract:

    Fluorescence microscopy has enabled a dramatic development in modern biology. Due to its inherently weak signal, fluorescence microscopy is not only much noisier than photography, but also presented with Poisson-Gaussian noise where Poisson noise, or shot noise, is the dominating noise source. To get clean fluorescence microscopy images, it is highly desirable to have effective denoising algorithms and datasets that are specifically designed to denoise fluorescence microscopy images. While su…

    Date Created:
    2019-10-15
    Resource Type
    Presentation
  • Author(s):
    Gregory Timp, Eamonn Kennedy, Zhuxin Dong, Clare Tennant
    Abstract:

    Disclosed are then inorganic membranes having a defined topography that includes pores having a defined diameter of nanometer and sub-nanometer diameter. The thin membranes are resistant to protein denaturing agents, and may be employed in analytical and clinical methods for identifying single amino acid residues within the sequence of a protein and the pores are other than NspA pores. Methods for making a thin inorganic membrane with nanopore and sub-nanopore topography and conical cone stru…

    Date Created:
    2019-09-26
    Resource Type
    Document
  • Author(s):
    William Philllip, Siyi Qu, Sherwood Benavides, Peng Gao, Feng Gao
    Abstract:

    A method for fabricating nanostructured polymeric materials based on a combination of inkjet printing and template synthesis. Layer-by-layer assembled nanotubes can be synthesized in a polycarbonate track-etched (PCTE) membrane by printing poly(allylamine hydrochloride) (PAH) and poly(styrenesulfonate) (PSS) sequentially. By changing the printing conditions, polymeric nanotubes or nanowires can be prepared by printing poly(vinyl alcohol) (PVA) in a PCTE template. Inkjet printing paired with t…

    Date Created:
    2019-08-20
    Resource Type
    Document
  • Author(s):
    Gregory Timp, Eamonn Kennedy, Zhuxin Dong, Clare Tennant
    Abstract:

    Disclosed are then inorganic membranes having a defined topography that includes pores having a defined diameter of nanometer and sub-nanometer diameter. The thin membranes are resistant to protein denaturing agents, and may be employed in analytical and clinical methods for identifying single amino acid residues within the sequence of a protein and the pores are other than NspA pores. Methods for making a thin inorganic membrane with nanopore and sub-nanopore topography and conical cone stru…

    Date Created:
    2019-02-28
    Resource Type
    Document
  • Author(s):
    Gregory Timp, Eamonn Kennedy
    Abstract:

    Disclosed are then inorganic membranes having a defined topography that includes pores having a defined diameter of nanometer and sub-nanometer diameter. The thin membranes are resistant to protein denaturing agents, and may be employed in analytical and clinical methods for identifying single amino acid residues within the sequence of a protein and the pores are other than NspA pores. Methods for making a thin inorganic membrane with nanopore and sub-nanopore topography and conical cone stru…

    Date Created:
    2019-02-28
    Resource Type
    Document
  • Abstract:

    The present invention relates to DNAzymes (also known as deoxyribozymes, DNA enzymes, catalytic DNA, or DZ), which are conjugated to nanoparticles (NP) to facilitate the detection of nucleic acids. One aspect of the invention relates to compounds comprising DNAzymes conjugated to nanoparticles (DZ-NP), such as metallic or gold nanoparticles, and methods for their synthesis. Another aspect of the invention relates to methods of using the conjugated compounds to detect nucleic acids, such as ge…

    Date Created:
    2019-08-07
    Resource Type
    Document
  • Author(s):
    Yide Zhang
    Abstract:

    In cancer and all biomedical researches, we always need a microscope with better imaging precision, speed, functionality, and depth, so that the diagnostics and treatments of cancer and other diseases can be accurate, fast, and noninvasive. However, conventional fluorescence microscopes cannot satisfy these needs due to physical limits on resolution, speed, information, and depth. In this work, we aim to overcome these limits using novel super-resolution microscopy and high-speed quantitative…

    Date Created:
    2018-04-09
    Resource Type
    Presentation
  • Author(s):
    Angela Chesler
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2018-08-15
    Resource Type
    Document
  • Author(s):
    Angela Chesler
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2018-08-15
    Resource Type
    Document
  • Author(s):
    Tracy Kijewski-Correa, Debra Javeline
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2018-05-22
    Resource Type
    Document
  • Author(s):
    Debra Javeline, Tracy Kijewski-Correa
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2017-06-13
    Resource Type
    Document