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  • Author(s):
    Yide Zhang
    Abstract:

    In cancer and all biomedical researches, we always need a microscope with better imaging precision, speed, functionality, and depth, so that the diagnostics and treatments of cancer and other diseases can be accurate, fast, and noninvasive. However, conventional fluorescence microscopes cannot satisfy these needs due to physical limits on resolution, speed, information, and depth. In this work, we aim to overcome these limits using novel super-resolution microscopy and high-speed quantitative…

    Date Created:
    2018-04-09
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang, Scott S. Howard, Cody J. Smith
    Abstract:

    Super-resolution microscopy is broadening our in-depth understanding of cellular structure. However, super-resolution approaches are limited, for numerous reasons, from utilization in longer-term intravital imaging. We devised a combinatorial imaging technique that combines deconvolution with stepwise optical saturation microscopy (DeSOS) to circumvent this issue and image cells in their native physiological environment. Other than a traditional confocal or two-photon microscope, this approac…

    Date Created:
    2019-01-09
    Resource Type
    Software
  • Author:
    Katie Ann-Marie Bugyis
    Advisory Committee:
    Margot Fassler, Peter Jeffery, Kathryn Kerby-Fulton, Mary Catherine Hilkert, John Van Engen
    Degree Area:
    Medieval Studies
    Degree:
    PhD
    Defense Date:
    2015-03-24
  • Author:
    Hailey Jane LaVoy
    Advisory Committee:
    Thomas F. X. Noble, Daniel Sheerin, John Van Engen, W. Martin Bloomer
    Degree Area:
    Medieval Studies
    Degree:
    PhD
    Defense Date:
    2015-03-23
  • Author:
    Michele Anik Stanbury
    Advisory Committee:
    David OConnor, Gretchen Reydams-Schils, Sean Kelsey, Stephen Gersh
    Degree Area:
    Medieval Studies
    Degree:
    PhD
    Defense Date:
    2014-11-14
  • Author:
    Lauren Linn Whitnah
    Advisory Committee:
    Daniel Hobbins, Hildegund Muller, Amy Mulligan, John Van Engen
    Degree Area:
    Medieval Studies
    Degree:
    PhD
    Defense Date:
    2014-08-29
  • Abstract:

    This session at CNI Fall Forum 2013 provides Notre Dame’s experience as a case study to provision research data curation and access services. Managing research outputs becomes a tall order of many universities, given their determined agenda to pursue research excellence. In a world of increasingly data-intensive research, data are rising as a critical component of scholarly communication, often mandated by granting agencies. Data curation, preservation, and access are paramount to the univers…

    Date Created:
    2013-12-13
    Resource Type
    Presentation
  • Author:
    Erik A. Koenke
    Advisory Committee:
    Randall Zachman, Joseph Wawrykow, Brad Gregory
    Degree Area:
    Medieval Studies
    Degree:
    PhD
    Defense Date:
    2014-07-22
  • Author:
    Joshua Morton Robinson
    Advisory Committee:
    Stephen Gersh, Alexandros Alexakis, Yury Avvakumov, Brian Daley, Charles Barber
    Degree Area:
    Medieval Studies
    Degree:
    PhD
    Defense Date:
    2014-04-25
  • Author:
    Stephen Reid Case
    Advisory Committee:
    Michael Crowe, Marvin Bolt, Christopher Hamlin, James Turner
    Degree Area:
    History and Philosophy of Science
    Degree:
    PhD
    Defense Date:
    2014-07-10
  • Author:
    Ana Velitchkova
    Advisory Committee:
    Lyn Spillman, Robert Fishman, Omar Lizardo, Ann Mische
    Degree Area:
    Peace Studies, Sociology
    Degree:
    PhD
    Defense Date:
    2014-06-24
  • Abstract:

    Presentation given at Open Repositories 2014 in Finland on the community Hydramata project that is building a shared application framework for institutional repositories based on Hydra.

    We are all facing rapidly changing repository demands that call for maximizing flexibility and interoperability among a heterogeneous network of technologies, varied workflows and wide array of evolving formats that are pushing the limits of our Institutional Repository technology. We need a repository to sup…

    Date Created:
    2014-05-29
    Resource Type
    Presentation