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  • Inventor(s):
    Hsueh-Chia Chang, David T. Leighton
    Patent Number:
    US 6428754 B2
    Description:

    An exhaust gas treatment system and method for treating the exhaust gas of an internal combustion engine includes a catalytic converter and a catalytic preheater or igniter upstream of the catalytic converter. A bypass passage extends around the igniter such that during the ignition period about two-thirds of the exhaust gas is bypassed around the igniter and one-third passes through the igniter. The igniter raises the temperature of the exhaust gases passing therethrough to an adiabatic temp…

    Date Issued:
    2002-08-06
    Resource Type
    Patent
  • Inventor(s):
    Hsueh-Chia Chang, Shau-Chun Paul Wang, Dmitri Lastochkin, Leslie Yeo, Zachary Gagnon
    Patent Number:
    US 8267914 B1
    Description:

    The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, oste…

    Date Issued:
    2012-09-18
    Resource Type
    Patent
  • Inventor(s):
    Hsueh-Chia Chang, Zilin Chen, Fu-Chih Hsu, David Battigelli
    Patent Number:
    US 7960180 B2
    Description:

    Methods and apparatus to capture and release microbe particles using amino-functionalized silica substrates are described. An example apparatus adapted to capture a microbe particle includes a silica substrate and a positively charged material to at least partially coat the silica substrate. The positive charged material includes an aminopropyl functional group.

    Date Issued:
    2011-06-14
    Resource Type
    Patent
  • Inventor(s):
    Zachary Gagnon, Hsueh-Chia Chang
    Patent Number:
    US 7744738 B2
    Description:

    The present invention provides a method and apparatus for use in rapid particle transportation, separation, focusing, characterization, and release. Dielectrophoresis and electro-osmotic driven fluid convection are used independently or in tandem as the driving forces for particle manipulation and on occasion characterization. Although dielectrophoresis has been acknowledged for decades as a powerful technique for particle manipulation and characterization, long processing times and measureme…

    Date Issued:
    2010-06-29
    Resource Type
    Patent
  • Inventor(s):
    Nishant Chetwani, Catherine Cassou, David Go, Hsueh-Chia Chang
    Patent Number:
    US 8716675 B2
    Description:

    An alternating current electrospray mass spectrometry device includes an electrospray device having at least one emitter providing a passageway for transmission of an analyte sample. At least one conductive element is in electrical communication with the at least one emitter. A power source generates an alternating current electric field to form a liquid cone at a tip of the emitter and ionizes the analyte sample present in the liquid cone. The frequency of the electric field entrains low mob…

    Date Issued:
    2014-05-06
    Resource Type
    Patent