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    Article

    Effects of mechanobiological signaling in bone marrow on skeletal health
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    Author(s):
    Kimberly Curtis, Alyssa Oberman, Glen Niebur
    Abstract:

    Bone marrow is a cellular tissue that forms within the pore space and hollow diaphysis of bones. As a tissue, its primary function is to support the hematopoietic progenitor cells that maintain the populations of both erythroid and myeloid lineage cells in the bone marrow, making it an essential element of normal mammalian physiology. However, bone’s primary function is load bearing, and deformations induced by external forces are transmitted to the encapsulatedmarrow.Understanding the effect…

    Date Published:
    2019-08
    Record Visibility:
    Public
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