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  • Author(s):
    Justin Stoler, Danice Brown Guzman, Ellis A. Adams
    Abstract:

    Many water, sanitation, and hygiene (WASH) interventions have traditionally implemented monitoring and evaluation plans that use a narrow set of WASH indicators that reflect a 20th-century prioritization of microbiological water quality as the most important proxy for WASH intervention success. Even when water is microbiologically safe, there are often substantial structural, behavioral, and institutional barriers to access. Measures of WASH intervention success should incorporate these impac…

    Date Created:
    2022-09-15
    Record Visibility:
    Public
    Resource Type
    Brief
  • Abstract:

    On a quarterly basis, the Kroc Institute produces independent, impartial, and academically rigorous information on the status of the implementation of the Final Accord. The quarterly reports aim to promote implementation processes and public dialogue and are presented to government and non-government entities in charge of implementation, civil society organizations, the international community, and all other parties committed or interested in this process.

    Date Created:
    2022-08-25
    Record Visibility:
    Public
    Resource Type
    Report
  • Author(s):
    Matthew Sisk
    Abstract:

    An XLSForm samlple survey. Designed for use with ArcGIS Survey123

    Date Created:
    2022-08-23
    Record Visibility:
    Public
    Resource Type
    Manuscript
  • Author(s):
    Sangnam Kim, Siyuan Zhang, Sangpil Yoon
    Abstract:

    Current advances in ultrasound imaging techniques combined with the next generation contrast agents such as gas vesicles (GV) revolutionize the visualization of biological tissues with spatiotemporal precision. In optics, fluorescent proteins enable understanding of molecular and cellular functions in biological systems due to their multiplexed imaging capability. Here, a panel of GVs is investigated using mid-band fit (MBF) spectral imaging to realize multiplexed ultrasound imaging to unique…

    Date Created:
    2022-08-11
    Record Visibility:
    Public
  • Author(s):
    Yide Zhang, Yinhao Zhu, Evan Nichols, Qingfei Wang, Vignesh Sundaresan, Siyuan Zhang, Cody Smith, Paul W. Bohn, Scott S. Howard
    Abstract:

    Fluorescence microscopy imaging speed is fundamentally limited by the measurement signal-to-noise ratio (SNR). To improve image SNR for a given image acquisition rate, computational denoising techniques can be used to suppress noise.However, common techniques to estimate a denoised image froma single frame either are computationally expensive or rely on simple noise statistical models. These models assume Poisson or Gaussian noise statistics, which are not appropriate for many fluorescence mi…

    Date Published:
    2022-03
    Record Visibility:
    Public
  • Author(s):
    Brant D. Gates, Jackson B. Vyletel, Lei Zou, Matthew Webber
    Abstract:

    The affinity possible from certain supramolecular motifs rivals that for some of the best-recognized interactions in biology. Cucurbit [7] uril (CB[7]) macrocycles, for example, are capable of achieving affinities in their binding to certain guests that rival that of biotin−avidin. Supramolecular host−guest recognition between CB[7] and certain guests has been demonstrated to spatially localize guest-linked agents to desired sites in vivo, offering opportunities to better exploit this affinit…

    Date Published:
    2022-06
    Record Visibility:
    Public
  • Author(s):
    Sally Sharif, Madhav Joshi
    Abstract:

    Policy Brief No. 12

    Since the end of the Cold War, twenty-four civil wars have ended in rebel victory. New rebel governments face existential threats both internally and externally. With rebel victory, international actors may quickly resort to putting pressure on former non-state actors to prevent renewed conflict. In addition, the structural factors that influence rebel victory in armed conflict, such as weak institutions, economic and political grievances, and arms availability, condition…

    Date Created:
    2022-08-09
    Record Visibility:
    Public
    Resource Type
    Brief
  • Author(s):
    Rothkopf, Ilana
    Abstract:

    Policy Brief No. 11

    How do peace agreements lead to new constitutions? Can constitutionalizing Comprehensive Peace Agreement (CPA) provisions supplement or reinforce CPAs? In countries emerging from civil conflict, constitutional reform is increasingly used as both a conflict-management and state-building mechanism. Nineteen of thirty-four (55.8%) CPAs in the Peace Accords Matrix (PAM) dataset include a provision for constitutional reform, and constitutional reform has been initiated to some…

    Date Created:
    2022-08-09
    Record Visibility:
    Public
    Resource Type
    Brief
  • Author(s):
    Zhihong Peng, Mohini Mohan Konai, Luis F. Avila-Cobian, Man Wang, Shahriar Mobashery, Mayland Chang
    Abstract:

    Idiopathic pulmonary fibrosis (IPF), a fatal disease characterized by excessive matrix degradation and fibrosis, destroys the lung architecture and results in the inability of the lungs to absorb oxygen. The cause(s) of IPF is unknown and current treatments are palliative. Matrix metalloproteinases (MMPs) and A Disintegrin And Metalloproteinases (ADAMs) likely play roles in IPF progression. However, specific MMPs and ADAMs in IPF have not been identified due to challenges in MMP/ADAM profilin…

    Date Published:
    2022-03
    Record Visibility:
    Public
  • Author(s):
    Brant D. Gates, Jackson B. Vyletel, Lei Zou, Matthew Webber
    Abstract:

    The affinity possible from certain supramolecular motifs rivals that for some of the best-recognized interactions in biology. Cucurbit [7] uril (CB[7]) macrocycles, for example, are capable of achieving affinities in their binding to certain guests that rival that of biotin−avidin. Supramolecular host−guest recognition between CB[7] and certain guests has been demonstrated to spatially localize guest-linked agents to desired sites in vivo, offering opportunities to better exploit this affinit…

    Date Published:
    2022-06
    Record Visibility:
    Public
  • Author(s):
    Josefina Echavarría, Cécile Mouly
    Abstract:

    Policy Brief No. 7

    This brief focuses on influential factors for turning Comprehensive Peace Agreements (CPAs) into sustainable platforms for nonviolent social and political change following internal armed conflict. Taking an extensive look at peace processes involving CPAs, the authors recommend that accord negotiators anticipate implementation challenges and set priorities for accord provisions. In addition, negotiators and mediators should include safeguards in the text of peace agreement…

    Date Created:
    2022-08-09
    Record Visibility:
    Public
    Resource Type
    Brief
  • Author(s):
    L. Gallagher, W. T. Barker, V. B. Hubble, J. Gasper, C. Melander, C. Manoil
    Abstract:

    Small molecule adjuvants that enhance the activity of established antibiotics represent promising agents in the battle against antibiotic resistance. Adjuvants generally act by inhibiting antibiotic resistance processes, and specifying the process acted on is a critical step in defining an adjuvant’s mechanism of action. This step is typically carried out biochemically by identifying molecules that bind adjuvants and then inferring their roles in resistance. Here, we present a complementary g…

    Date Published:
    2022-01
    Record Visibility:
    Public