University of Notre Dame
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- Author(s):
- Paige Alexander, Josefina Echavarría Alvarez, Roddy Brett, Victoria K. Holt, Louisa Lombard, Monica McWilliams, Catherine Panter-Brick, Enrica Picco, Honey Thomas, Alexander Thurston, Jason Quinn, Bisa Williams
- Abstract:
This brief draws on case studies of civil war to consider how sustainable peacebuilding can be practiced. The authors take the view that peace agreements mark the beginning, not the end, of a process of national reform and reconciliation in both the institutional and normative spheres. Peace agreements, when properly designed, have the potential to do more for a country than put an end to the immediate violence; they can present a turning point.
- Date Created:
- 2023-02-28
- Record Visibility:
- Public
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- Author(s):
- David Cortright, Anna Romandash
- Abstract:
The latest edition of the global Women Peace and Security Index draws on recognized data sources to measure women’s inclusion, justice, and security. From a total of 170 countries, Iraq came in at 166. Within the Middle East and North Africa region, Iraq ranked third lowest, with only Syria and Yemen behind. The position of women within Iraqi society has deteriorated rapidly since the 1991 Gulf War. Women and girls were disproportionately affected by the economic consequences of sanctions. Th…
- Date Created:
- 2023-02-28
- Record Visibility:
- Public
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3
Presentation
- Author(s):
- Ebrahim Moosa
- Abstract:
In his inaugural lecture for the Mirza Family Professorship of Islamic Thought and Muslim Societies, Ebrahim Moosa explores how the concept of progress has been understood in Islamic thought and the challenges that this notion of progress poses to European and American conceptualizations of the term. Beginning with a biographical sketch of his grandfather in South Africa and Muzzafar Mirza, after whom the endowed chair for this inaugural address is named, Moosa traces in these lives and in th…
- Date Created:
- 2023-02-17
- Record Visibility:
- Public
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- Author(s):
- Jessica Morales, Anastasia Guimaraes
- Abstract:
This chapter offers a glimpse into using an integrated project-management approach to migrate from a legacy homegrown system to a vendor-supported electronic resource management (ERM) system supported by a user community. Regardless of the level of project management adoption at one’s institution, the readers will gain insight into how project management can create great value by efficiently organizing the work, improving communication through intentional planning, and meeting deadlines throu…
- Date Created:
- 2022-08-12
- Record Visibility:
- Public
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- Author(s):
- Maria Carnovale, Ellis A. Adams
- Abstract:
This brief explores smart sanitation technology (SST) in a variety of low-to-middle income country contexts. While SST interventions are recognized as highly effective in community health settings, they come with many considerations that must be weighed before their implementation. This report explores different SST interventions, the benefits and drawbacks to each, and related public health and policy implications.
- Date Created:
- 2023-02-08
- Record Visibility:
- Public
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- Author(s):
- Bradley D. Smith
- Abstract:
A broad array of imaging and diagnostic technologies employs fluorophore-labeled antibodies for biomarker visualization, an experimental technique known as immunofluorescence. Significant performance advantages, such as higher signal-to-noise ratio, are gained if the appended fluorophore emits near-infrared (NIR) light with a wavelength >700 nm. However, the currently available NIR fluorophore antibody conjugates are known to exhibit significant limitations, including low chemical stabilit…
- Date Published:
- 2021-02
- Record Visibility:
- Public
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7
Article
- Author(s):
- Allen G. Oliver, Bradley D. Smith
- Abstract:
A new supramolecular paradigm is presented for reliable capture and co-precipitation of haloauric acids (HAuX4) from organic solvents or water. Two classes of acyclic organic compounds act as complementary receptors (tectons) by forming two sets of directional non-covalent interactions, (a) hydrogen bonding between amide (or amidinium) NH residues and the electronegative X ligands on the AuX4 @, and (b) electrostatic stacking of the electron deficient Au center against the face of an aromatic…
- Date Published:
- 2020-06
- Record Visibility:
- Public
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- Author(s):
- Dong-Hao Li, Cynthia L. Schreiber, Bradley D. Smith
- Abstract:
The near-infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is deep penetration of the light and negligible background fluorescence. However, dye instability, aggregation, and poor pharmacokinetics are current drawbacks that limit performance and the scope of possible applications. All these limitations are simultaneously overcome with a new molecular design strategy that produces a charge balanced and sterically shielded fluorochrome…
- Date Published:
- 2020-07
- Record Visibility:
- Public
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- Author(s):
- Canjia Zhai, Cynthia L. Schreiber, Sasha Padilla-Coley, Allen G. Oliver, Bradley D. Smith
- Abstract:
A general synthetic method creates a new class of covalently connected, self-threaded, fluorescent molecular probes with figure-eight topology, an encapsulated deep-red fluorophore, and two peripheral peptide loops. The globular molecular shape and rigidified peptide loops enhance imaging performance by promoting water solubility, eliminating probe self-aggregation, and increasing probe stability. Moreover, the peptide loops determine the affinity and selectivity for targets within complex bi…
- Date Published:
- 2020-01
- Record Visibility:
- Public
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- Author(s):
- Canjia Zhai, Cynthia L. Schreiber, Sasha Padilla-Coley, Allen G. Oliver, Bradley D. Smith
- Abstract:
A general synthetic method creates a new class of covalently connected, self-threaded, fluorescent molecular probes with figure-eight topology, an encapsulated deep-red fluorophore, and two peripheral peptide loops. The globular molecular shape and rigidified peptide loops enhance imaging performance by promoting water solubility, eliminating probe self-aggregation, and increasing probe stability. Moreover, the peptide loops determine the affinity and selectivity for targets within complex bi…
- Date Published:
- 2020-01
- Record Visibility:
- Public
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- Author(s):
- Dong-Hao Li, Cynthia L. Schreiber, Bradley D. Smith
- Abstract:
The near-infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is deep penetration of the light and negligible background fluorescence. However, dye instability, aggregation, and poor pharmacokinetics are current drawbacks that limit performance and the scope of possible applications. All these limitations are simultaneously overcome with a new molecular design strategy that produces a charge balanced and sterically shielded fluorochrome…
- Date Published:
- 2020-07
- Record Visibility:
- Public
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- Author(s):
- Bradley D. Smith
- Abstract:
Macrocyclic hosts have long been used for guest encapsulation, and recently a new application has emerged; employment as supramolecular elements for capture and recovery of gold through host/guest co-precipitation. The guests are square-planar tetrahaloaurate anions, practically important gold complexes with a capacity to engage in non-covalent interactions such as hydrogen bonding and Au–! interactions. The successful macrocyclic hosts for co-precipitation include cyclodextrins, cucurbituril…
- Date Published:
- 2021-01
- Record Visibility:
- Public