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  • Inventor(s):
    Hsueh-Chia Chang, Zilin Chen, Fu-Chih Hsu, David Battigelli
    Patent Number:
    US 7960180 B2
    Description:

    Methods and apparatus to capture and release microbe particles using amino-functionalized silica substrates are described. An example apparatus adapted to capture a microbe particle includes a silica substrate and a positively charged material to at least partially coat the silica substrate. The positive charged material includes an aminopropyl functional group.

    Date Issued:
    2011-06-14
    Resource Type
    Patent
  • Inventor(s):
    Mehul Patel, Thomas C. Corke
    Patent Number:
    US 7954768 B2
    Description:

    A method of controlling an aircraft, missile, munition or ground vehicle with plasma actuators, and more particularly of controlling fluid flow across their surfaces or other surfaces which would benefit from such a method, includes the design of an aerodynamic plasma actuator for the purpose of controlling airflow separation over a control surface of a aircraft, missile, or a ground vehicle, and a method of determining a modulation frequency for the plasma actuator for the purpose of fluid f…

    Date Issued:
    2011-06-07
    Resource Type
    Patent
  • Inventor(s):
    John H. Adams, Malcolm J. Fraser, Bharath Balu, Douglas A. Shoue
    Patent Number:
    US 7932088 B2
    Description:

    The present invention provides molecular methods for efficiently transforming the genome of common disease-transmitting parasites, such as Plasmodium falciparum. The transformation efficiencies are improved up to 100 times over those conventionally known. The methods provide high saturation of the target parasite genome, of 50% or greater, and target non-specifically TTAA-rich sites in the parasite genome. The invention also discloses a model that may be used to functionally annotate the geno…

    Date Issued:
    2011-04-26
    Resource Type
    Patent
  • Inventor(s):
    Mijoon Lee, Masahiro Ikejiri, Mayland Chang, Rafael Fridman, Shahriar Mobashery
    Patent Number:
    US 7928127 B2
    Description:

    The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.

    Date Issued:
    2011-04-19
    Resource Type
    Patent
  • Inventor(s):
    Allen H. Simpson, Slawomir T. Fryska, Mark L. La Forest, Roger L. Klinedinst, Alexander Mukasyan
    Patent Number:
    US 7922845 B2
    Description:

    An apparatus for bonding a first carbon composite to a second carbon composite through a reactant layer includes a housing, and a pair of conductive press plates electrically isolated from the housing. The press plates are adapted to position the two parts to be bonded with a reactant layer therebetween. The press plates are subjected to an electrical potential and a clamping force, sufficient to initiate a combustion reaction that creates a molten ceramic to bond together the carbon-carbon c…

    Date Issued:
    2011-04-12
    Resource Type
    Patent
  • Inventor(s):
    Eric Matlis, Scott Morris, Thomas C. Corke, Joshua Cameron
    Patent Number:
    US 7908115 B2
    Description:

    Plasma sensors, systems and related methods are described. An example method for predicting an event includes providing a carrier signal across two electrodes and forming a plasma between the two electrodes. The example method also includes measuring a modulated signal from the plasma, manipulating the modulated signal to produce a value and comparing the value to a threshold. Finally, the example method includes determining the likelihood of the event based on the comparison.

    Date Issued:
    2011-03-15
    Resource Type
    Patent
  • Inventor(s):
    Rudolph M. Navari, Mary Prorok, Francis J. Castellino
    Patent Number:
    US 7892750 B2
    Description:

    Elevated levels of cathepsin E (catE) are demonstrated to be diagnostic of intestinal forms of cancer, such as colorectal cancer. Elevated levels of cathepsin E (catE, monomeric forms) are demonstrated to be detectable in the urine of animals having colorectal cancer, and a diagnostic/screening method for identifying and/or detecting colorectal in an animal from a urine sample is provided. Specific tissue immunohistochemcial staining for catE (monomeric forms) in dysplastic tissue is also dis…

    Date Issued:
    2011-02-22
    Resource Type
    Patent
  • Inventor(s):
    Jean-Baptiste Thibault, Charles A. Bouman, Jeffrey Allen Fessler, Ken D. Sauer
    Patent Number:
    US 7885371 B2
    Description:

    A method and system for image reconstruction of data acquired by a device such as computed tomography is provided. The method and system use a multi-stage statistical iterative reconstruction techniques to provide a three dimensional representation of the scanned object. In one embodiment, the first stage uses a projection-based reconstruction technique, such as Ordered Subset (OS) to converge on a solution for low frequency portion of the image. A subsequent stage uses a voxel-based reconstr…

    Date Issued:
    2011-02-08
    Resource Type
    Patent
  • Inventor(s):
    Allen H. Simpson, Slawomir T. Fryska, Mark L. La Forest, Alexander Mukasyan
    Patent Number:
    US 7858187 B2
    Description:

    Method of joining carbon-carbon composite pieces together, e.g. in the refurbishment of aircraft brake discs. The method includes the steps of: providing a first carbon-carbon composite piece and a second carbon-carbon composite piece, wherein the second carbon-carbon composite piece has a surface that is complementary to a surface of said first carbon-carbon composite piece; providing a layer of a mixture of titanium powder and carbon powder on the first complementary mating surface; arrangi…

    Date Issued:
    2010-12-28
    Resource Type
    Patent
  • Inventor(s):
    Jeffrey W. Talley, Steven Larson, Lawrence G. Wolfe, Brian D. Fisher
    Patent Number:
    US 8748331 B2
    Description:

    A method of manufacturing a remediation material uses a biogenic material as a substrate and involves preparing the surface of the substrate to enable a chemical reaction, and performing template-driven surface derivatization on the substrate to provide a net positive charge on the substrate. The remediation material may be placed into contact with surface water, ground water, soil, or sediment by at least one of a permeable reactive barrier, direct well injection, or direct introduction of t…

    Date Issued:
    2014-06-10
    Resource Type
    Patent
  • Inventor(s):
    Luis A. Montestruque, Michael D. Lemmon, Jeffrey W. Talley
    Patent Number:
    US 7792126 B2
    Description:

    A distributed monitoring and control system includes a plurality of nodes forming a redundant communication network. Each of the nodes includes a processor, a memory and a transceiver. At least one of the nodes includes a sensor for acquiring information. At least one of the nodes includes an actuator. At least one of the processors is programmed with a control algorithm to receive information acquired from the sensors, calculate a control command and communicate the control command to the ac…

    Date Issued:
    2010-09-07
    Resource Type
    Patent
  • Inventor(s):
    Zachary Gagnon, Hsueh-Chia Chang
    Patent Number:
    US 7744738 B2
    Description:

    The present invention provides a method and apparatus for use in rapid particle transportation, separation, focusing, characterization, and release. Dielectrophoresis and electro-osmotic driven fluid convection are used independently or in tandem as the driving forces for particle manipulation and on occasion characterization. Although dielectrophoresis has been acknowledged for decades as a powerful technique for particle manipulation and characterization, long processing times and measureme…

    Date Issued:
    2010-06-29
    Resource Type
    Patent