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  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
    Patent Number:
    US 8268874 B2
    Description:

    Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in…

    Date Issued:
    2012-09-18
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski
    Patent Number:
    US 8362268 B2
    Description:

    Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.

    Date Issued:
    2013-01-29
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
    Patent Number:
    US 8729270 B2
    Description:

    Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in…

    Date Issued:
    2014-05-20
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
    Patent Number:
    US 9309238 B2
    Description:

    Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.

    Date Issued:
    2016-04-12
    Resource Type
    Patent
  • Inventor(s):
    Garrett C. Moraski, Marvin J. Miller
    Patent Number:
    US 9605002 B2
    Description:

    The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,…

    Date Issued:
    2017-03-28
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski
    Patent Number:
    US 9617249 B2
    Description:

    Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.

    Date Issued:
    2017-04-11
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
    Patent Number:
    US 9908876 B2
    Description:

    Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.

    Date Issued:
    2018-03-06
    Resource Type
    Patent