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  • Author(s):
    Rashida Callender, Joally M.Canales, Carolina Avendano, Elena Craft, Katherine B. Ensor, Marie Lynn Miranda
    Abstract:

    Objectives To assess the economic and mental health impacts of COVID-19 in the presence of previous exposure to flooding events.

    Methods Starting in April 2018, the Texas Flood Registry (TFR) invited residents to complete an online survey regarding their experiences with Hurricane Harvey and subsequent flooding events. Starting in April 2020, participants nationwide were invited to complete a brief online survey on their experiences during the pandemic. This study includes participan…

    Date Published:
    2022-08
    Record Visibility:
    Public
  • Author(s):
    Mercedes A. Bravo, Dominique Zephyr, Katherine Ensor, Daniel Kowal, Marie Lynn Miranda
    Abstract:

    Racial/ethnic disparities in academic performance may result from a confluence of adverse exposures that arise from structural racism and accrue to specific subpopulations. This study investigates childhood lead exposure, racial residential segregation, and early educational outcomes. Geocoded North Carolina birth data is linked to blood lead surveillance data and fourth-grade standardized test scores (n = 25,699). We constructed a census tract-level measure of racial isolation (RI) of the no…

    Date Published:
    2022-08
    Record Visibility:
    Public
  • Author(s):
    Samantha M. Hall, Sharon Zhang, Kate Hoffman, Marie Lynn Miranda, Heather M. Stapleton
    Abstract:

    Per- and polyfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants commonly detected in human serum. Previous studies have observed associations between maternal serum PFAS and adverse pregnancy and birth outcomes such as lower birth weight or pre-eclampsia; however, few studies have explored these associations with birth outcomes and placental tissue PFAS concentration. The placenta is a vital contributor to a healthy pregnancy and may be involved in the mechanism of PFAS r…

    Date Published:
    2022-05
    Record Visibility:
    Public
  • Author(s):
    Shan Zhou, Robert J. Griffin, Alex Bui, Aaron Lilienfeld Asbun, Mercedes A. Bravo, Claire Osgood, Marie Lynn Miranda
    Abstract:

    Studies increasingly use output from the Environmental Protection Agency’s Fused Air Quality Surface Downscaler (“downscaler”) model, which provides spatial predictions of daily concentrations of fine particulate matter (PM2.5) and ozone (O3) at the census tract level, to study the health and societal impacts of exposure to air pollution. Downscaler outputs have been used to show that lower income and higher minority neighborhoods are exposed to higher levels of PM2.5 and lower …

    Date Published:
    2022-05
    Record Visibility:
    Public
  • Author(s):
    Mercedes A. Bravo, Joshua L. Warren, Man Chong Leong, Nicole C. Deziel, Rachel T. Kimbro, Michelle L. Bell, Marie Lynn Miranda
    Abstract:

    In the United States, concentrations of criteria air pollutants have declined in recent decades. Questions remain regarding whether improvements in air quality are equitably distributed across subpopulations. We assessed spatial variability and temporal trends in concentrations of particulate matter with an aerodynamic diameter ≤2.5 μm (PM2.5) and ozone (O3) across North Carolina from 2002–2016, and associations with community characteristics. Estimated daily PM2.5 and O3 concentrations at 20…

    Date Published:
    2022-04
    Record Visibility:
    Public
  • Author(s):
    Steven J. Krieg, Carolina Avendano, Evan Grantham-Brown, Aaron Lilienfeld Asbun, Jennifer J. Schnur, Marie Lynn Miranda, Nitesh V. Chawla
    Abstract:

    COVID-19 remains a global threat in the face of emerging SARS-CoV-2 variants and gaps in vaccine administration and availability, and organizations must be prepared to detect and mitigate its risk to their people and activities. In this report we share key lessons learned from an adaptive COVID-19 testing program implemented at a mid-sized university in the Midwest. The program utilized two simple, diverse, and easily interpretable machine learning models to quickly and accurately predict whi…

    Date Published:
    2022-02
    Record Visibility:
    Public
  • Author(s):
    Carolina Avendano, Aaron Lilienfeld, Liz Rulli, Melissa Stephens, Wendy Alvarez Barrios, Joseph Sarro, Michael E. Pfrender, Marie Lynn Miranda
    Abstract:

    Importance: The COVID-19 pandemic led many higher education institutions to close campuses during the 2020-2021 academic year. As campuses prepared for a return to in-person education, many institutions were mandating vaccines for students and considering the same for faculty and staff.

    Objective: To determine the association between vaccination coverage and the levels and spread of SARS-CoV-2, even in the presence of highly-transmissible variants and congregate living, at a midsized unive…

    Date Published:
    2022-02
    Record Visibility:
    Public
  • Author(s):
    Bonnie R. Joubert, Marianthi-Anna Kioumourtzoglou, Toccara Chamberlain, Hua Yun Chen, Chris Gennings, Mary E. Turyk, Marie Lynn Miranda, Thomas F. Webster, Katherine B. Ensor, David B. Dunson, Brent A. Coull
    Abstract:

    Humans are exposed to a diverse mixture of chemical and non-chemical exposures across their lifetimes. Well-designed epidemiology studies as well as sophisticated exposure science and related technologies enable the investigation of the health impacts of mixtures. While existing statistical methods can address the most basic questions related to the association between environmental mixtures and health endpoints, there were gaps in our ability to learn from mixtures data in several common epi…

    Date Published:
    2022-01
    Record Visibility:
    Public
  • Author(s):
    Mercedes A. Bravo, Marie Lynn Miranda
    Abstract:

    Background: Previous studies observed associations between prenatal exposure to fine particulate matter (≤ 2.5 μm; PM2.5) and small-for-gestational-age (SGA) birth and lower birthweight percentile for gestational age. Few, if any, studies examine prenatal air pollution exposure and these pregnancy outcomes in neonates born to the same women. Here, we assess whether prenatal exposure to ambient fine particulate matter (PM2.5) is associated with small-for-gestational-age (SGA) birth or birthwe…

    Date Published:
    2022-01
    Record Visibility:
    Public
  • Author(s):
    Ji-Young Son, Marie Lynn Miranda, Michelle L. Bell
    Abstract:

    Concentrated animal feeding operations (CAFOs) have emerged as an environmental justice issue due to disproportionate siting in low-income and minority communities. However, CAFOs’ impact on health is not fully understood. We examined risk of cause-specific mortality associated with CAFOs in North Carolina (NC) for 2000-2017 and health disparities. We obtained data on individual-level cause-specific mortality and on permitted animal facilities. We estimated associations between exposure to CA…

    Date Published:
    2021-12
    Record Visibility:
    Public
  • Author(s):
    Merick M. Yamada, Michael B. Rosamilia, Karen E. Chiswell, Alfred D'Ottavio, Tracy Spears, Claire Osgood, Marie Lynn Miranda, Nina Forestieri, Jennifer S. Li, Andrew P. Landstrom
    Abstract:

    Background: Sudden infant death syndrome (SIDS) is the sudden, unexplained death of infants <1 year old. SIDS remains a leading cause of death in US infants. We aim to identify associations between SIDS and race/ethnicity, birth weight/gestational age, and socioeconomic/environmental factors in North Carolina (NC) to help identify infants at risk for SIDS.

    Methods and Results: In this IRB-approved study, infant mortality 2007–2016 and death certificate-linked natality 2007–2014 were obtai…

    Date Published:
    2021-12
    Record Visibility:
    Public
  • Author(s):
    Mercedes A.Bravo, Marie Lynn Miranda
    Abstract:

    Abstract Background Persistent disparities in academic performance may result from a confluence of adverse exposures accruing disproportionately to specific subpopulations.

    Objective Our overarching objective was to investigate how multiple exposures experienced over time affect early childhood educational outcomes. We were specifically interested in whether there were: racial/ethnic disparities in prevalence of adverse exposures; racial/ethnic disparities in associations observed between ad…

    Date Published:
    2021-07
    Record Visibility:
    Public