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- Inventor(s):
- Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
- Patent Number:
- US 8268874 B2
- Description:
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in…
- Date Issued:
- 2012-09-18
- Title
- Anti-cancer compounds, synthesis thereof, and methods of using same
- Description
- Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in a subject, such as using the disclosed heterocyclic anti-cancer agents.
- Creator
- Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
- Publisher
- United States Patent and Trademark Office
- Language
- eng
- Rights
- http://creativecommons.org/publicdomain/zero/1.0/
- Resource Type
- Patent
-
- Inventor(s):
- Marvin J. Miller, Garrett C. Moraski
- Patent Number:
- US 8362268 B2
- Description:
Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.
- Date Issued:
- 2013-01-29
- Title
- Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria
- Description
- Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.
- Creator
- Marvin J. Miller, Garrett C. Moraski
- Publisher
- United States Patent and Trademark Office
- Language
- eng
- Rights
- http://creativecommons.org/publicdomain/zero/1.0/
- Resource Type
- Patent
-
- Inventor(s):
- Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
- Patent Number:
- US 8729270 B2
- Description:
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in…
- Date Issued:
- 2014-05-20
- Title
- Anti-cancer compounds, synthesis thereof, and methods of using same
- Description
- Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in a subject, such as using the disclosed heterocyclic anti-cancer agents.
- Creator
- Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
- Publisher
- U.S. Patent and Trademark Office
- Language
- English
- Rights
- http://creativecommons.org/publicdomain/zero/1.0/
- Resource Type
- Patent
-
- Inventor(s):
- Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
- Patent Number:
- US 9309238 B2
- Description:
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.
- Date Issued:
- 2016-04-12
- Title
- Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same
- Description
- Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.
- Creator
- Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
- Publisher
- U.S. Patent and Trademark Office
- Language
- English
- Rights
- All rights reserved
- Resource Type
- Patent
-
- Inventor(s):
- Garrett C. Moraski, Marvin J. Miller
- Patent Number:
- US 9605002 B2
- Description:
The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,…
- Date Issued:
- 2017-03-28
- Title
- 5,5-heteroaromatic anti-infective compounds
- Description
- The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,1-b]thiazole-5-carbox- amide.
- Creator
- Garrett C. Moraski, Marvin J. Miller
- Publisher
- U.S. Patent and Trademark Office
- Language
- English
- Rights
- All rights reserved
- Resource Type
- Patent
-
- Inventor(s):
- Marvin J. Miller, Garrett C. Moraski
- Patent Number:
- US 9617249 B2
- Description:
Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.
- Date Issued:
- 2017-04-11
- Title
- Benzoheterocyclic anti-bacterial agents
- Description
- Embodiments herein provide compounds and methods of making and using such compounds for prevention and treatment of multidrug resistant bacteria. In particular, embodiments are directed to anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria.
- Creator
- Marvin J. Miller, Garrett C. Moraski
- Publisher
- U.S. Patent and Trademark Office
- Language
- English
- Rights
- All rights reserved
- Resource Type
- Patent
-
- Inventor(s):
- Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
- Patent Number:
- US 9908876 B2
- Description:
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.
- Date Issued:
- 2018-03-06
- Title
- Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same
- Description
- Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same. Disclosed herein are various imidazo[1,2-a]pyhdine compounds and methods of using the novel compounds to treat or prevent tuberculosis in a subject or to inhibit fungal growth on plant species. Other embodiments include methods of synthesizing imidazo[1,2-a]pyridine compounds, such as the disclosed imidazo[1,2-a]pyridine compounds.
- Creator
- Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
- Publisher
- U.S. Patent and Trademark Office
- Language
- English
- Rights
- All rights reserved
- Resource Type
- Patent