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  • Author(s):
    Margo Waters, Veronica Kalwajtys, Katelyn Carothers, Ryan Roeder, Joshua Shrout, Shaun Lee, Prakash Nallathamby
    Abstract:

    The increasing frequency of nosocomial infections caused by antibiotic-resistant microorganisms concurrent with the stagnant discovery of new classes of antibiotics has made the development of new antibacterial agents a critical priority. Our approach is an antibiotic-free strategy drawing inspiration from bacteriophages to combat antibiotic-resistant bacteria. We developed a nanoparticle-based antibacterial system that structurally mimics the protein-turret distribution on the head structure…

    Date Published:
    2019-10
    Record Visibility:
    Public
  • Author(s):
    Yide Zhang, Prakash Nallathamby, Genevieve D. Vigil, Aamir A. Khan, Devon E. Mason, Joel D. Boerckel, Ryan K. Roeder, Scott S. Howard
    Abstract:

    Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the super-resolution microscopy is not feasible in many applications. In this paper, we propose and demonstrate a saturation-based super-resolution fluorescence microscopy technique that can be easily implemented and requires neither additional hardware nor complex post-processin…

    Date Published:
    2018-04
    Record Visibility:
    Public