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  • Inventor(s):
    Mayland Chang, Shahriar Mobashery, Mijoon Lee
    Patent Number:
    US 9867805 B2
    Description:

    The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinases (MMPs). The disease, disorder, or condition can include, for example, stroke, neurological disorders, or ophthalmological disorders. The treatment can include administering a compound or composition described herein, thereby providing a prodrug compound that metabolizes to an active MMP inhibitor in vivo. The MMP inhibition can be …

    Date Issued:
    2018-01-16
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Mayland Chang, Shahriar Mobashery
    Patent Number:
    US 9951035 B2
    Description:

    The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinases (MMPs). The compounds can be selective MMP inhibitors, for example, selective inhibitors of MMP-2, MMP-9, and/or MMP-14. The disease, disorder, or condition can include, for example, stroke, neurological disorders, ophthalmological disorders, or wounds, such as chronic wounds or diabetic wounds.

    Date Issued:
    2018-04-24
    Record Visibility:
    Public
    Resource Type
    Patent