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  Patent

  Method and apparatus for AC electrospray
  

  Inventor(s):

  Hsueh-Chia Chang, Shau-Chun Paul Wang, Dmitri Lastochkin, Leslie Yeo, Zachary Gagnon

  Patent Number:

  US 8267914 B1

  Description:

  The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, oste…

  Date Issued:

  2012-09-18

  Record Visibility:

  Public

  Title

  Method and apparatus for AC electrospray

  Description

  The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, osteogenic or dermatological growth factors, bacteria, viruses, immobilized enzyme receptors and fluorescent particles for controlled release drug delivery, tissue or bone engineering, clinical or environmental field testing and as biosensors for clinical or drug monitoring. In addition, the present invention may be used to synthesize biodegradable fibers as bioscaffolds for tissue engineering, surgical sutures or medical gauze that enhance blood coagulation, and further may be encapsulated by other agents.

  Creator

  Hsueh-Chia Chang, Shau-Chun Paul Wang, Dmitri Lastochkin, Leslie Yeo, Zachary Gagnon

  Publisher

  United States Patent and Trademark Office

  Language

  eng

  Rights

  http://creativecommons.org/publicdomain/zero/1.0/

  Resource Type

  Patent