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  • Inventor(s):
    Marvin J. Miller
    Patent Number:
    US 4595532 B2
    Description:

    N-Mono or N-disubstituted methyl-2-azetidinones are provided via cyclization of .beta.-hydroxy or .beta.-halo substituted acid sec-amides wherein the amide nitrogen is substituted with a mono- or di-substituted methyl group having activating substituents. Cyclization of .beta.-hydroxy acid amides is mediated by triphenylphosphine-dialkylazodicarboxylate while cyclization of .beta.-halo acid amides is mediated by strong bases e.g. lithium dialkylamides. E.g. Diethyl amino-protected L-serylamin…

    Date Issued:
    1986-06-17
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Arthur H. Hale, Peringandoor R. Hariharan, Sanjit Roy
    Patent Number:
    US 5637795 B2
    Description:

    A novel process and apparatus have been contrived for the study of the bit/stabilizer balling phenomenon in the laboratory. The device permits a standard testing procedure using a specially designed bob simulating the drill bit for comparing degrees of balling for different rock formations under different drilling conditions involving variable and controlled parameters like weight-on-bit, revolutions-per-minute (rpm), drilling fluids, etc.

    Date Issued:
    1997-06-10
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    James J. Carberry, Charles Benjamin Alcock
    Patent Number:
    US 5286698 B2
    Description:

    Solid oxide solutions of the formula La.sub.1-x Sr.sub.x CrO.sub.3-.differential. have been found to exhibit surprisingly high specific activity as catalysts for oxidation and hydrogenation reactions. The oxide solutions can be utilized in particulate form or applied as films to the surfaces of refractory substrates. The oxide solution catalysts are expected to be a viable alternative to the noble metal catalysts now used commercially for treatment of combustion chamber exhaust gases to reduc…

    Date Issued:
    1994-02-15
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Paul J. McGinn, Hongmei An
    Patent Number:
    US 8356475 B2
    Description:

    Described is a method of slowly releasing a catalyst for, inter alia, the purpose of soot oxidation in a particulate filter. An example method includes incorporating an alkali metal oxide in a glass. Slow leaching of the alkali from the glass provides a means to gradually deliver the catalyst over extended periods. Additionally, the example method includes increasing the amount of alkaline metal ions that may be leached from the glass.

    Date Issued:
    2013-01-22
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Gaetano Francis D'Alelio
    Patent Number:
    US 3890274 B2
    Description:

    Phthalonitrile-terminated aromatic polyimides and polyimide-phthalocyanines are provided. The phthalonitrile-terminated polyimides are prepared by reacting an anhydride end-capped, aromatic polyimide with at least two moles of a dicyano aromatic monoamine to give a polyimide of the structural formula: ##SPC1## Wherein Ar is a divalent aromatic organic radical, Ar’ is a tetravalent aromatic organic radical, the four carbonyl groups being attached directly to separate carbon atoms and each …

    Date Issued:
    1975-06-17
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Steven Ruggiero, Carol Tanner
    Patent Number:
    US 8456635 B2
    Description:

    Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transm…

    Date Issued:
    2013-06-04
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Gaetano Francis D'Alelio
    Patent Number:
    US 4026904 B2
    Description:

    Aromatic epoxy-terminated aromatic polyimides and processes for their preparation are provided. The epoxidized polyimides are prepared by epoxidizing an olefinically unsaturated aromatic imide of the formula: ##STR1## WHEREIN Ar is a divalent aromatic organic radical, Ar’ is a tetravalent aromatic organic radical, the four carbonyl groups being attached directly to separate carbon atoms and each pair of carbonyl groups being attached to adjacent carbon atoms in the Ar’ radical, R’…

    Date Issued:
    1977-05-31
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Matthew A. Williams
    Patent Number:
    US 5106968 B2
    Description:

    1-Carbapenam-2-one-3-carboxylic acid and 1-carba-3-hydroxy-3-cephem-4-carboxylic acid and esters thereof are provided by a process comprising a rhodium C.sub.2 -C.sub.10 carboxylate catalyzed cyclization of an ester of a 4-(1-alkoxy- or 1-substituted alkoxy)-2-oxo-4-azetidinyl)-.beta.-ketobutyric acid and an ester of a 5-(1-alkoxy- or 1-substituted alkoxy-2-oxo-4-azetidinyl)-.alpha.-diazo-.beta.-ketovaleric acid respectively. The process is carried out in an inert organic solvent at a tempera…

    Date Issued:
    1992-04-21
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Yanping Xu
    Patent Number:
    US 6310058 B2
    Description:

    Compounds represented by the formula [1] ##STR1## R.sub.1 is H or a substituent; R.sub.2 and R.sub.3 are C.sub.1 -C.sub.3 alkyl; R.sub.4 is siderophore group e.g. CH.sub.3 –(CH.sub.2).sub.n –C(O)–N(OH)–(CH.sub.2).sub.m – with n=10-22, m=2-6; X is O, S, or NH; X.sub.1 is O or NH; Y is H or alkyl; Z is H or substituted amino, e.g., t-BocNH or CbzNH, and r is 2-4; are useful in the method provided for treating tuberculosis. [1] is prepared by coupling [7], wherein HX.sub.1 is HO– or H.sub….

    Date Issued:
    2001-10-30
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller
    Patent Number:
    US 5266468 B2
    Description:

    .beta.-Hydroxy-.alpha.-amino acids are obtained via serine hydroxymethyltransferase catalyzed condensation of aldehydes with glycine. The predominant product with most aldehydes is the L-erythro diastereomer. For example, succinic semialdehyde methylester is condensed with glycine in the process to provide L-erythro .alpha.-amino hydroxy adipic acid mono methyl ester.

    Date Issued:
    1993-11-30
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller
    Patent Number:
    US 4675399 B2
    Description:

    Process for N-acyloxy or sulfooxy 2-azetidinones comprising O-acylation of a .beta.-hydroxy or .beta.-halo hydroxamic acid, and cyclizing the O-acylhydroxamate with TPP-CCl.sub.4 -TEA or with TPP-dialkylazodicarboxylate to the N-acyloxy-2-azetidinone. Solvolysis of the acyl group provides an N-hydroxy-2-azetidinone. e.g., N-Cbz-L-serine is converted to the O-acetyl hydroxamate, cyclized and solvolyzed to N-hydroxy-3-(Cbz-amino)-2-azetidinone. The N-hydroxy-2-azetidinones are useful intermedia…

    Date Issued:
    1987-06-23
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    John G. Duman
    Patent Number:
    US 5627051 B2
    Description:

    The present invention is directed to nucleic acid sequences encoding Dendroides canadensis thermal hysteresis proteins. The THPs of Dendroides have significantly greater thermal hysteresis activity than any other known anti-freeze protein. The thermal hysteresis activity of the purified THPs can be further enhanced by combining the THPs with various “activating” compounds.

    Date Issued:
    1997-05-06
    Record Visibility:
    Public
    Resource Type
    Patent