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  • Author(s):
    Gergo Szakmany, Alexei Orlov, Gary Bernstein, Wolfgang Porod
    Abstract:

    This paper reports a two-orders-of-magnitude improvement in the sensitivity of antenna-coupled nanothermocouple (ACNTC) infrared detectors. The electrical signal generated by on-chip ACNTCs results from the temperature difference between a resonant antenna locally heated by infrared radiation and the substrate. A cavity etched under the antenna provides two benefits. It eliminates the undesirable cooling of the hot junction by thermally isolating the antenna from the substrate. More important…

    Date Published:
    2019-07
  • Author(s):
    Zhuxin Dong, Jae Hyde Park, Eamonn Kennedy, Mohammad Hokmabadi, Lisa Almonte-Garcia, Li Ding, Narayana Aluru, Gregory Timp
    Abstract:

    The size of an ion affects everything from the structure of water to life itself. In this report, to gauge their size, ions dissolved in water are forced electrically through a sub-nanometer- diameter pore spanning a thin membrane and the current is measured. The measurements reveal an ion-selective conductance that vanishes in pores <0.24 nm in diameter—the size of a water molecule—indicating that permeating ions have a grossly distorted hydration shell. Analysis of the current noise powe…

    Date Published:
    2019-05
  • Author(s):
    Eveline Rigo, Zhuzin Dong, Jae Hyun Park, Eamonn Kennedy, Mohammad Hokmabadi, Lisa Almonte-Garcia, Li Ding, Narayana Aluru, Gregory Timp
    Abstract:

    The size of an ion affects everything from the structure of water to life itself. In this report, to gauge their size, ions dissolved in water are forced electrically through a sub-nanometer- diameter pore spanning a thin membrane and the current is measured. The measurements reveal an ion-selective conductance that vanishes in pores <0.24 nm in diameter—the size of a water molecule—indicating that permeating ions have a grossly distorted hydration shell. Analysis of the current noise powe…

  • Author(s):
    Cassandra L. Gorsuch, Patrick Fagan, Chan Lee, Sun Eun Kim, Jens C. Hamann, Joshua A. Mason, Kelsey J. Weigel, Matyas Abel Tsegaye, Luqun Shen, Sydney Shuff, Junjun Zuo, Stephan Hu, Lei jJiang, Sarah Chapman, W. Matthew Leevy, Ralph J. DeBerardinis, Michael Overholtzer, Zachary T. Schafer
    Abstract:

    For cancer cells to survive during extracellular matrix (ECM) detachment, they must inhibit anoikis and rectify metabolic deficiencies that cause non-apoptotic cell death. Previous studies in ECM-detached cells have linked non-apoptotic cell death to reactive oxygen species (ROS) generation, although the mechanistic underpinnings of this link remain poorly defined. Here, we uncover a role for receptor-interacting protein kinase 1 (RIPK1) in the modulation of ROS and cell viability during ECM …

    Date Published:
    2018-03