Notre Dame Patents

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Description

This collection brings together all of the patents assigned to the University of Notre Dame from 1952 to the present, plus other selected patents prior to 1952. Each record includes a full-text searchable and accessible PDF document for the corresponding invention. The record also includes the present-day academic department with which the inventor was or would have been associated.

Why patents? According to the University’s IDEA Center, “Part of the University’s public service mission is to ensure that the results of its research are made available for public use and benefit. This is accomplished in many ways: through educating students, publishing results of research, and ensuring that inventions are developed into useful products and services for the benefit of the public.”

“Today, our research universities play an even more vital role in creating a better future—not only by educating close to 600,000 graduate students in science and engineering every year, but also, and critically, by performing more than 15% of U.S. R&D in 2011—and according to 2012 NSF data, accounted for the majority (53%) of national basic research. This research, some basic, some applied or ‘translational’ creates new technologies, new products and services, medicines, diagnostics — the list is long and impressive — but also, this research gives rise to entire new industries.” (David Winwood, “The Importance of Patents and Academic Technology Transfer,” March 26, 2015)

The collection also includes the most famous patent associated with Notre Dame, U.S. patent 1,811,959 from 1931, “Vinyl derivatives of acetylene and method of preparing the same” — in other words, synthetic rubber. Invented by Rev. Fr. Julius Nieuwland, CSC, and assigned to DuPont, this patent did, in fact, give rise to entire new industries. More about this invention may be found at the National Inventors Hall of Fame.

These patents are one more example of the University fulfilling Rev. Fr. Sorin’s vision of becoming a “powerful force for good.”

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  • Inventor(s):
    Crislyn D'Souza-Schorey, James W. Clancy, Vandhana Muralidharan-Chari
    Patent Number:
    US 9329188 B2
    Description:

    The present application relates to the isolation and analysis of populations of microvesicles and the identification of invasive microvesicles in the populations such as populations of microvesicles that are shed by tumor cells. Invasive microvesicles from tumor cells contain a variety of specific proteins, such as ARF6.

    Date Issued:
    2016-05-03
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Jeffrey S. Schorey, Karen M. Dobos
    Patent Number:
    US 9255924 B2
    Description:

    The invention provides methods for the detection of M. tuberculosis proteins in or on exosomes derived from infected individuals. The methods can use a proteomic approach including mass spectroscopy, data mining and multiplex reaction monitoring to quickly examine a large amount of M. tuberculosis proteins to determine the best biomarkers for use in diagnostic tests to identify active TB patients.

    Date Issued:
    2016-02-09
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Douglas C. Hall, Scott Howard, Anthony Hoffman, Gary H. Bernstein, Jason M. Kulick
    Patent Number:
    US 9620473 B1
    Description:

    First and second integrated devices each have an optical component and a plurality of interconnect structures disposed one edge thereon. The first edge surface of the second integrated device is positioned contiguous to the first edge surface of the first integrated device. The interconnect structures disposed on the first integrated device are in physical contact with the interconnect structures disposed on the edge surface of the second integrated device so as to provide alignment for conve…

    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Julius A. Nieuwland
    Patent Number:
    US 1811959
    Description:

    This invention relates to a process for controlling acetylene reactions and for bringing about the reaction of acetylene with other substances. More particularly it relates to the use of cuprous chloride in acetylene re-actions as a catalyst.

    (See also http://www.invent.org/honor/inductees/inductee-detail/?IID=111)

    Date Issued:
    1931-06-30
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Mark L. La Forest, Allen H. Simpson, Slawomir T. Fryska, Alexander Mukasyan
    Patent Number:
    US 8383197 B2
    Description:

    A metal powder is applied to the surface of the area of a carbon-carbon composite brake disc to be protected against migration of antioxidant. The metal powder may be titanium powder or tungsten powder. A chemical reaction between the metal powder and carbon is then initiated by heating the powder-coated brake to the ignition temperature via application of electric current (Joule preheating) or by heating it in a furnace. Upon combustion, the metal particles react with carbon in the composite…

    Date Issued:
    2013-02-26
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Ashley P. Thrall, Angelene J. Dascanio, Chad P. Quaglia
    Patent Number:
    US 9,334,645 B2
    Description:

    A shelter has a packaged configuration and a deployed configuration. The shelter has four panels, each with four edges and two faces. The first and fourth panels have a rectangular shape, and the second and third panels have a quadrangle shape. The relationship of panel edge lengths and angles of the quadrangle shelter panels create a sturdy enclosure that is easy to erect, manipulate, and reconfigure. Furthermore, the shelter may be erected by rotating the panels into place via pivotal conne…

    Date Issued:
    May 10, 2016
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Allen H. Simpson, Slawomir T. Fryska, Mark L. La Forest, Roger L. Klinedinst, Alexander Mukasyan, Charles D. D'Amico
    Patent Number:
    US 8448685 B2
    Description:

    An apparatus for bonding a first carbon composite to a second carbon composite through a reactant layer includes a housing, and a pair of conductive press plates electrically isolated from the housing. The press plates are adapted to position the two parts to be bonded with a reactant layer therebetween. The press plates are subjected to an electrical potential and a clamping force, sufficient to initiate a combustion reaction that creates a molten ceramic to bond together the carbon-carbon c…

    Date Issued:
    2013-05-28
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Nishant Chetwani, Catherine Cassou, David Go, Hsueh-Chia Chang
    Patent Number:
    US 8716675 B2
    Description:

    An alternating current electrospray mass spectrometry device includes an electrospray device having at least one emitter providing a passageway for transmission of an analyte sample. At least one conductive element is in electrical communication with the at least one emitter. A power source generates an alternating current electric field to form a liquid cone at a tip of the emitter and ionizes the analyte sample present in the liquid cone. The frequency of the electric field entrains low mob…

    Date Issued:
    2014-05-06
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Garrett C. Moraski, Jonathan Stefely
    Patent Number:
    US 8729270 B2
    Description:

    Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in…

    Date Issued:
    2014-05-20
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Kishore K. Pydimarry, Duane T. Detwiler, John E. Renaud, Neal M. Patel, Byungsoo Kang, Chandan K. Mozumder
    Patent Number:
    US 8880380 B2
    Description:

    Crashworthiness designing of a structure using a Hybrid Cellular Automata (HCA) algorithm where field states are computed using finite element analysis (FEA) and the material distribution of the structure is updated at each iteration using cellular automata method. The HCA algorithm optimizes the topology of the structures to achieve certain performance within the limits of various constraints applied to ensure crashworthiness of the structures. The HCA algorithm may also be applied to design…

    Date Issued:
    2014-11-04
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Hsueh-Chia Chang, Jason Gordon, Satyajyoti Senapati, Zachary Gagnon, Sagnik Basuray
    Patent Number:
    US 8771938 B2
    Description:

    Disclosed are example methods and devices for detecting one or more targets. An example method includes placing a sample including a first target with in a microfluidic device and hybridizing a plurality of copies of the first target with a plurality of nanostructures. The example method includes applying an electric current to the plurality of nanostructures and using an electric field created by the electric current to move the plurality of nanostructures. In addition, the plurality of nano…

    Date Issued:
    2014-07-08
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Mayland Chang, Shahriar Mobashery, Mijoon Lee
    Patent Number:
    US 8937151 B2
    Description:

    The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinases (MMPs). The disease, disorder, or condition can include, for example, stroke, neurological disorders, or ophthalmological disorders. The treatment can include administering a compound or composition described herein, thereby providing a prodrug compound that metabolizes to an active MMP inhibitor in vivo. The MMP inhibition can be …

    Date Issued:
    2015-01-20
    Record Visibility:
    Public
    Resource Type
    Patent