Notre Dame Patents

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Description

This collection brings together all of the patents assigned to the University of Notre Dame from 1952 to 2020, plus other selected patents prior to 1952. Each record includes a full-text searchable and accessible PDF document for the corresponding invention. The record also includes the present-day academic department with which the inventor was or would have been associated.

Why patents? According to the University’s IDEA Center, “Part of the University’s public service mission is to ensure that the results of its research are made available for public use and benefit. This is accomplished in many ways: through educating students, publishing results of research, and ensuring that inventions are developed into useful products and services for the benefit of the public.”

“Today, our research universities play an even more vital role in creating a better future—not only by educating close to 600,000 graduate students in science and engineering every year, but also, and critically, by performing more than 15% of U.S. R&D in 2011—and according to 2012 NSF data, accounted for the majority (53%) of national basic research. This research, some basic, some applied or ‘translational’ creates new technologies, new products and services, medicines, diagnostics — the list is long and impressive — but also, this research gives rise to entire new industries.” (David Winwood, “The Importance of Patents and Academic Technology Transfer,” March 26, 2015)

The collection also includes the most famous patent associated with Notre Dame, U.S. patent 1,811,959 from 1931, “Vinyl derivatives of acetylene and method of preparing the same” — in other words, synthetic rubber. Invented by Rev. Fr. Julius Nieuwland, CSC, and assigned to DuPont, this patent did, in fact, give rise to entire new industries. More about this invention may be found at the National Inventors Hall of Fame.

These patents are one more example of the University fulfilling Rev. Fr. Sorin’s vision of becoming a “powerful force for good.”

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  • Inventor(s):
    Abhay Kumar, Paul W. Futa, Jr., Steven F. Fisher
    Patent Number:
    US 6328056 B2
    Description:

    An unbalance compensated bypass valve (14, 21, 23) for a gas turbine engine fuel supply system is responsive to the fuel pressure differential across a fuel metering valve (15) to open and close a bypass orifice (37, 39, 41; 89, 91, 93; 99, 101, 103). The bypass valve (14, 21, 23) selectively supplies high fuel pressure to a compensating cavity (45, 95, 120) providing a counterbalancing force against an annular area (47, 97, 124) of the bypass valve piston (34, 81, 83, 111, 112) to compensate…

    Date Issued:
    2001-12-11
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Zhou Yu, Bruno Kristiaan Bernard De Man, Jean-Baptiste Thibault, Debashish Pal, Lin Fu, Charles A. Bouman, Ken D. Sauer, Sathish Ramani, Jeffrey Allen Fessler, Somesh Srivastava
    Patent Number:
    US 8885975 B2
    Description:

    A method is provided for reconstructing an image of an object that includes image elements. The method includes accessing measurement data associated with the image elements, introducing an auxiliary variable to transform an original problem of reconstructing the image to a constrained optimization problem, and solving the constrained optimization problem using a method of multipliers to create a sequence of sub-problems and solve the sequence of sub-problems. Solving the sequence of sub-prob…

    Date Issued:
    2014-11-11
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Allen H. Simpson, Slawomir T. Fryska, Mark L. La Forest, Alexander Mukasyan
    Patent Number:
    US 7858187 B2
    Description:

    Method of joining carbon-carbon composite pieces together, e.g. in the refurbishment of aircraft brake discs. The method includes the steps of: providing a first carbon-carbon composite piece and a second carbon-carbon composite piece, wherein the second carbon-carbon composite piece has a surface that is complementary to a surface of said first carbon-carbon composite piece; providing a layer of a mixture of titanium powder and carbon powder on the first complementary mating surface; arrangi…

    Date Issued:
    2010-12-28
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Olaf G. Wiest, Paul Helquist, Frederick R. Maxfield
    Patent Number:
    US 9333222 B2
    Description:

    Embodiments herein relate to the field of lysosomal storage disorders, and, more specifically, to methods of treating lysosomal storage disorders such as Niemann-Pick type C disease, for instance with inhibitors of histone deacetylases, particularly inhibitors of class 1 histone deacetylases. In various embodiments, methods of treating Niemann-Pick type C disease with inhibitors of class 1 histone deacetylases are described.

    Date Issued:
    May 10, 2016
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller
    Patent Number:
    US 4595532 B2
    Description:

    N-Mono or N-disubstituted methyl-2-azetidinones are provided via cyclization of .beta.-hydroxy or .beta.-halo substituted acid sec-amides wherein the amide nitrogen is substituted with a mono- or di-substituted methyl group having activating substituents. Cyclization of .beta.-hydroxy acid amides is mediated by triphenylphosphine-dialkylazodicarboxylate while cyclization of .beta.-halo acid amides is mediated by strong bases e.g. lithium dialkylamides. E.g. Diethyl amino-protected L-serylamin…

    Date Issued:
    1986-06-17
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Tommie L. Wood, Thomas C. Corke, Martiqua Post
    Patent Number:
    US 8308112 B2
    Description:

    An aircraft includes a surface over which an airflow passes. A plasma actuator is configured to generate a plasma above the surface, the plasma coupling a directed momentum into the air surrounding the surface to reduce separation of the airflow from the surface. A method of reducing separation of an airflow from a surface of an aircraft includes generating a plasma in air surrounding the surface at a position where the airflow would separate from the surface in the absence of the plasma.

    Date Issued:
    2012-11-13
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Bradley D. Smith, Arunkumar Easwaran
    Patent Number:
    US 8273875 B2
    Description:

    Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to novel near-infrared dyes that are photostable and resistant to quenching. The dyes belong to a novel family of squaraine rotaxanes, and they are particularly well-suited for use in biological applications. Also disclosed are methods of synthesizing the dyes and methods of using the dyes.

    Date Issued:
    2012-09-25
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller, Yanping Xu
    Patent Number:
    US 6310058 B2
    Description:

    Compounds represented by the formula [1] ##STR1## R.sub.1 is H or a substituent; R.sub.2 and R.sub.3 are C.sub.1 -C.sub.3 alkyl; R.sub.4 is siderophore group e.g. CH.sub.3 –(CH.sub.2).sub.n –C(O)–N(OH)–(CH.sub.2).sub.m – with n=10-22, m=2-6; X is O, S, or NH; X.sub.1 is O or NH; Y is H or alkyl; Z is H or substituted amino, e.g., t-BocNH or CbzNH, and r is 2-4; are useful in the method provided for treating tuberculosis. [1] is prepared by coupling [7], wherein HX.sub.1 is HO– or H.sub….

    Date Issued:
    2001-10-30
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller
    Patent Number:
    US 4675399 B2
    Description:

    Process for N-acyloxy or sulfooxy 2-azetidinones comprising O-acylation of a .beta.-hydroxy or .beta.-halo hydroxamic acid, and cyclizing the O-acylhydroxamate with TPP-CCl.sub.4 -TEA or with TPP-dialkylazodicarboxylate to the N-acyloxy-2-azetidinone. Solvolysis of the acyl group provides an N-hydroxy-2-azetidinone. e.g., N-Cbz-L-serine is converted to the O-acetyl hydroxamate, cyclized and solvolyzed to N-hydroxy-3-(Cbz-amino)-2-azetidinone. The N-hydroxy-2-azetidinones are useful intermedia…

    Date Issued:
    1987-06-23
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    John G. Duman
    Patent Number:
    US 5627051 B2
    Description:

    The present invention is directed to nucleic acid sequences encoding Dendroides canadensis thermal hysteresis proteins. The THPs of Dendroides have significantly greater thermal hysteresis activity than any other known anti-freeze protein. The thermal hysteresis activity of the purified THPs can be further enhanced by combining the THPs with various “activating” compounds.

    Date Issued:
    1997-05-06
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Marvin J. Miller
    Patent Number:
    US 5266468 B2
    Description:

    .beta.-Hydroxy-.alpha.-amino acids are obtained via serine hydroxymethyltransferase catalyzed condensation of aldehydes with glycine. The predominant product with most aldehydes is the L-erythro diastereomer. For example, succinic semialdehyde methylester is condensed with glycine in the process to provide L-erythro .alpha.-amino hydroxy adipic acid mono methyl ester.

    Date Issued:
    1993-11-30
    Record Visibility:
    Public
    Resource Type
    Patent
  • Inventor(s):
    Logeshwaran Vijayan, Sundaram Vanka, Partha Sarathy Murali, Phanimithra Gangalakurthi
    Patent Number:
    US 8107518 B2
    Description:

    A process for equalizing streams of OFDM subcarrier data computes the noise variance for each stream, and forms a stream weighting coefficient by equalizing the noise variance, such that for a first stream having a noise variance .sigma..sub.1 and a second stream having a noise variance of .sigma..sub.2, the first stream is scaled by .times..sigma..sigma..sigma. ##EQU00001## and the second stream is scaled by .times..sigma..sigma..sigma. ##EQU00002##

    Date Issued:
    2012-01-31
    Record Visibility:
    Public
    Resource Type
    Patent