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  • Author(s):
    Peggy Griesinger, Mikala Narlock, Jeremy Friesen, Hanna Bertoldi
    Abstract:

    The presenters will outline efforts to create a unified discovery platform for digital collections from libraries, archives, and museums. They will guide attendees through the process of designing harmonized metadata profiles for these related but very different domains, including solutions for conciliating controlled vocabularies. They will discuss the software stack’s approach to moving the harmonized data from varied back-end systems to a singular point from which they build out multiple s…

    Date Created:
    2020-03-12
    Record Visibility:
    Public
    Resource Type
    Presentation
  • 2

    Presentation

    Author(s):
    Mikala Narlock
    Abstract:

    Since the publication of the “FAIR Guiding Principles for scientific data management and stewardship” (Wilkinson et al., 2016), a wide-variety of sciences, mathematics, and other data-intensive fields have utilized the principles to promote reusability of data and ensure the long-term preservation of valuable outputs. In particular, domain experts and leading researchers have organized hackathons and sprints to define FAIR for their specific domains. Similarly, these domain experts have creat…

    Date Created:
    2019-11-10
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Multiphoton microscopy combined with fluorescence lifetime imaging microscopy (MPM-FLIM) is a technique that allows for imaging the lifetime of fluorescence created by two-photon excitation. It not only possesses the advantages of MPM such as large imaging depth, but also the strengths of FLIM including the ability to discriminate different fluorophores with similar emission spectra. In FLIM, the frequency-domain (FD) method, which relies on periodic intensity-modulated excitation light and i…

    Date Created:
    2015-10-22
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    In cancer and all biomedical researches, we always need a microscope with better imaging precision, speed, functionality, and depth, so that the diagnostics and treatments of cancer and other diseases can be accurate, fast, and noninvasive. However, conventional fluorescence microscopes cannot satisfy these needs due to physical limits on resolution, speed, information, and depth. In this work, we aim to overcome these limits using novel super-resolution microscopy and high-speed quantitative…

    Date Created:
    2018-04-09
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Multiphoton microscopy (MPM) is a widely used in vivo imaging technique in biological and medical applications. In the case of two-photon excitation fluorescence, two lower-energy photons excite a fluorophore which in turn emits a single higher-energy photon, whose rate depends quadratically on the excitation intensity, thus enabling higher resolution with narrower point spread function (PSF) than conventional one-photon fluorescence microscopy. Fluorescence lifetime imaging microscopy (FLIM)…

    Date Created:
    2016-04-04
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    To fundamentally understand biological and medical phenomena such as aging and diseases, we need the information of the microenvironment surrounding living cells. We propose the multiphoton fluorescence lifetime imaging microscopy (MPM-FLIM) platform with super-sensitivity and super-resolution capabilities to quantitatively obtain this information at the intracellular level. First, we present a simple MPM oxygen imaging probe compatible with aqueous biological media based on water-soluble rut…

    Date Created:
    2017-03-30
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Yide Zhang
    Abstract:

    Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit, but its universal application is not feasible due to its difficult implementation and high cost. In this research, we propose and demonstrate a new kind of super-resolution fluorescence microscopy that can be easily implemented and requires neither additional hardware nor complex post-processing. The microscopy is based on the principle o…

    Date Created:
    2017-10-19
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Angela Chesler
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2018-08-15
    Record Visibility:
    Public
    Resource Type
    Document
  • Author(s):
    Angela Chesler
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2018-08-15
    Record Visibility:
    Public
    Resource Type
    Document
  • Author(s):
    Tracy Kijewski-Correa, Debra Javeline
    Abstract:

    As climate changes, coastal homeowners are potentially crucial actors in reducing the risks to property and human life from rising seas and increased hurricane activity. Absent strict, enforceable regulations mandating retrofitting of existing homes or major changes in homeowner insurance requirements, coastal resilience in a changing climate will largely reflect private, voluntary decisions of millions of individuals. However, research is scarce on the current risk level of U.S. coastal home…

    Date Created:
    2018-05-22
    Record Visibility:
    Public
    Resource Type
    Document
  • Author(s):
    Mandy Havert, Jonathan D. Schwarz
    Abstract:

    The iconic Hesburgh Library building was nearing its 50th anniversary when review of the facilities program began in advance of renovation planning. This talk centers on graduate student workspaces, in particular closed study carrels that were characterized as ‘mop closets’ by some occupants. In 2013, review of existing data and feedback informed the initial planning for renovation of one tower floor in the library and its graduate student spaces. Through a series of focus groups, ope…

    Date Created:
    2017-10-10
    Record Visibility:
    Public
    Resource Type
    Presentation
  • Author(s):
    Mandy Havert
    Abstract:

    Do you struggle with locating your files? Is it nearly impossible for you to find and retrieve articles and content that you’ve saved on a moment’s notice? Does your bookmark file look like a junk drawer from the kitchen or garage? Are you still storing 17 drafts of that paper you completed, turned in, edited, resubmitted and received a final grade on years ago because you don’t remember which paper-final-final-final.doc is the actual final copy?

    If yes is the answer to any of these questio…

    Date Created:
    2016-09-27
    Record Visibility:
    Public
    Resource Type
    Presentation