Articles & Publications
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List of files deposited in CurateND that match your search criteria
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- Author(s):
- Georgina Curto
- Abstract:
Among the myriad of technical approaches and abstract guidelines proposed to the topic of AI bias, there has been an urgent call to translate the principle of fairness into the operational AI reality with the involvement of social sciences specialists to analyze the context of specific types of bias, since there is not a generalizable solution. This article ofers an interdisciplinary contribution to the topic of AI and societal bias, in particular against the poor, providing a conceptual fram…
- Date Created:
- 2023-03-24
- Record Visibility:
- Public
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- Author(s):
- Jessica Morales, Anastasia Guimaraes
- Abstract:
This chapter offers a glimpse into using an integrated project-management approach to migrate from a legacy homegrown system to a vendor-supported electronic resource management (ERM) system supported by a user community. Regardless of the level of project management adoption at one’s institution, the readers will gain insight into how project management can create great value by efficiently organizing the work, improving communication through intentional planning, and meeting deadlines throu…
- Date Created:
- 2022-08-12
- Record Visibility:
- Public
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- Author(s):
- John M. Golden, Thomas H. Lee
- Abstract:
This Article sheds new light on the private rights/public rights distinction used by the Supreme Court to assess the extent to which the United States Constitution permits adjudication by a non-Article III federal tribunal. State courts have traditionally been the primary deciders of lawsuits over private rights—historically defined as suits regarding “the liability of one individual to another under the law as defined.” If Congress could limitlessly assign adjudication of private rights case…
- Date Published:
- 2022
- Record Visibility:
- Public
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- Author(s):
- Eric Chaisson
- Abstract:
A new way is proposed to thermodynamically gauge the evolving complexity of nation-states and their growing cities. Energy rate density is a useful metric to track the evolution of energy budgets, which help facilitate how well or badly human society trends toward winning or losing. The fates of nations and their cities are unknown, their success is not assured. Those nations and cities with rising per-capita energy usage while developing and those that are nearly flat while already developed…
- Date Published:
- 2022
- Record Visibility:
- Public
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- Author(s):
- Harvey Brown
- Abstract:
This paper is concerned with the nature of probability in physics, and in quantum mechanics in particular. It starts with a brief discussion of the evolution of Itamar Pitowsky’s thinking about probability in quantum theory from 1994 to 2008, and the role of Gleason’s 1957 theorem in his derivation of the Born Rule. Pitowsky’s defence of probability therein as a logic of partial belief leads us into a broader discussion of probability in physics, in which the existence of objectiv…
- Date Published:
- 2020
- Record Visibility:
- Public
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- Author(s):
- Bradley D. Smith
- Abstract:
A broad array of imaging and diagnostic technologies employs fluorophore-labeled antibodies for biomarker visualization, an experimental technique known as immunofluorescence. Significant performance advantages, such as higher signal-to-noise ratio, are gained if the appended fluorophore emits near-infrared (NIR) light with a wavelength >700 nm. However, the currently available NIR fluorophore antibody conjugates are known to exhibit significant limitations, including low chemical stabilit…
- Date Published:
- 2021-02
- Record Visibility:
- Public
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19
Article
- Author(s):
- Allen G. Oliver, Bradley D. Smith
- Abstract:
A new supramolecular paradigm is presented for reliable capture and co-precipitation of haloauric acids (HAuX4) from organic solvents or water. Two classes of acyclic organic compounds act as complementary receptors (tectons) by forming two sets of directional non-covalent interactions, (a) hydrogen bonding between amide (or amidinium) NH residues and the electronegative X ligands on the AuX4 @, and (b) electrostatic stacking of the electron deficient Au center against the face of an aromatic…
- Date Published:
- 2020-06
- Record Visibility:
- Public
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- Author(s):
- Dong-Hao Li, Cynthia L. Schreiber, Bradley D. Smith
- Abstract:
The near-infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is deep penetration of the light and negligible background fluorescence. However, dye instability, aggregation, and poor pharmacokinetics are current drawbacks that limit performance and the scope of possible applications. All these limitations are simultaneously overcome with a new molecular design strategy that produces a charge balanced and sterically shielded fluorochrome…
- Date Published:
- 2020-07
- Record Visibility:
- Public
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- Author(s):
- Canjia Zhai, Cynthia L. Schreiber, Sasha Padilla-Coley, Allen G. Oliver, Bradley D. Smith
- Abstract:
A general synthetic method creates a new class of covalently connected, self-threaded, fluorescent molecular probes with figure-eight topology, an encapsulated deep-red fluorophore, and two peripheral peptide loops. The globular molecular shape and rigidified peptide loops enhance imaging performance by promoting water solubility, eliminating probe self-aggregation, and increasing probe stability. Moreover, the peptide loops determine the affinity and selectivity for targets within complex bi…
- Date Published:
- 2020-01
- Record Visibility:
- Public
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- Author(s):
- Canjia Zhai, Cynthia L. Schreiber, Sasha Padilla-Coley, Allen G. Oliver, Bradley D. Smith
- Abstract:
A general synthetic method creates a new class of covalently connected, self-threaded, fluorescent molecular probes with figure-eight topology, an encapsulated deep-red fluorophore, and two peripheral peptide loops. The globular molecular shape and rigidified peptide loops enhance imaging performance by promoting water solubility, eliminating probe self-aggregation, and increasing probe stability. Moreover, the peptide loops determine the affinity and selectivity for targets within complex bi…
- Date Published:
- 2020-01
- Record Visibility:
- Public
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- Author(s):
- Dong-Hao Li, Cynthia L. Schreiber, Bradley D. Smith
- Abstract:
The near-infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging because there is deep penetration of the light and negligible background fluorescence. However, dye instability, aggregation, and poor pharmacokinetics are current drawbacks that limit performance and the scope of possible applications. All these limitations are simultaneously overcome with a new molecular design strategy that produces a charge balanced and sterically shielded fluorochrome…
- Date Published:
- 2020-07
- Record Visibility:
- Public
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- Author(s):
- Bradley D. Smith
- Abstract:
Macrocyclic hosts have long been used for guest encapsulation, and recently a new application has emerged; employment as supramolecular elements for capture and recovery of gold through host/guest co-precipitation. The guests are square-planar tetrahaloaurate anions, practically important gold complexes with a capacity to engage in non-covalent interactions such as hydrogen bonding and Au–! interactions. The successful macrocyclic hosts for co-precipitation include cyclodextrins, cucurbituril…
- Date Published:
- 2021-01
- Record Visibility:
- Public